SH3BP5L and PLEKHA5

Number of citations of the paper that reports this interaction (PubMedID 20936779)
88

Data Source:
BioGRID (two hybrid)

		SH3BP5L	PLEKHA5
Description		SH3 binding domain protein 5 like	pleckstrin homology domain containing A5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleoplasm Cytosol Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Protein Kinase Inhibitor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Intracellular Signal Transduction Negative Regulation Of Protein Tyrosine Kinase Activity	Biological_process Reproductive System Development
Pathways			Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Lead levels ( 26025379)	Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Chronic mountain sickness ( 31417607) Daytime sleep phenotypes ( 27126917) Gut microbiota (bacterial taxa) ( 27694959) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Pharmacokinetics of antiepileptic drugs in severe mental disorder (concentration drug ratio) ( 25944848) Platelet reactivity in response to clopidogrel treatment ( 32472697) Thalamus volume ( 31530798)
Interacting Genes		10 interacting genes: CEP57 EMC2 FAM161B NINL PLEKHA5 RAB11B RAB14 RAB25 SUOX YWHAG	36 interacting genes: ADK ARHGEF9 BET1 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 H2AJ KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 RECQL SH3BP5L SOGA1 SPIRE1 SPTAN1 SPTBN1 SRPK2 UPF1 WASH2P YWHAG
Entrez ID		80851	54477
HPRD ID		13887	09684
Ensembl ID		ENSG00000175137	ENSG00000052126
Uniprot IDs		A0A024R0T2 Q7L8J4	A0A024RAY7 Q9HAU0
PDB IDs			2DKP
Enriched GO Terms of Interacting Partners?
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