TRAF3IP3 and OSBPL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRAF3IP3	OSBPL3
Description		TRAF3 interacting protein 3	oxysterol binding protein like 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Mitochondrial Outer Membrane Lysosomal Membrane Plasma Membrane Integral Component Of Membrane	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Nuclear Membrane Filopodium Tip Intracellular Membrane-bounded Organelle Perinuclear Endoplasmic Reticulum
	Molecular Function	Protein Binding	Protein Binding Sterol Transporter Activity Cholesterol Binding Sterol Binding
	Biological Process		Bile Acid Biosynthetic Process Sterol Transport
Pathways			Synthesis of bile acids and bile salts
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Orofacial clefts ( 33137956) Red blood cell count ( 32888494 27863252) Worry too long after an embarrassing experience ( 29500382)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Pursuit maintenance gain ( 29064472) Sulfasalazine-induced agranulocytosis ( 28762467)
Interacting Genes		47 interacting genes: ATG16L1 CBARP CCDC136 CCDC138 CCDC88B CCNC CDCA7L CEP68 CEP70 COQ9 CPLX4 CREB3L3 EBAG9 EMD EVI2B FAM209A FATE1 GOLGA6L9 GOLM2 GORAB GRAMD2A KASH5 KIR2DL3 KRT27 L3MBTL3 LIME1 LRRC25 MFF MINAR1 NDEL1 OSBPL3 PLEKHO1 PSTPIP1 RACGAP1 RIC3 RILPL1 SP100 STMN4 STX1A STX4 TFIP11 TMEM139 TRAF3 TRIM36 WAC ZNRD2 ZRANB1	26 interacting genes: ACSM1 BYSL FAM161A GABARAPL1 GABARAPL2 LNX1 MCRS1 PALS2 PLK4 PRPF18 PRPF3 RALGPS2 RPL11 STK35 SYTL4 TCEA2 TCEANC TRAF3IP3 WT1 YWHAB YWHAG ZBTB16 ZNF48 ZNF497 ZNF648 ZNF835
Entrez ID		80342	26031
HPRD ID		16305	09474
Ensembl ID		ENSG00000009790	ENSG00000070882
Uniprot IDs		B1AJU2 B3KWQ9 Q9Y228	Q9H4L5
PDB IDs			7CYZ
Enriched GO Terms of Interacting Partners?
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