ZKSCAN3 and SCAND1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZKSCAN3	SCAND1
Description		zinc finger with KRAB and SCAN domains 3	SCAN domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Autophagy Lysosome Organization Negative Regulation Of Autophagy Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Senescence	Positive Regulation Of Transcription, DNA-templated
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Hip circumference adjusted for BMI ( 34021172) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 28166213) Lung function (FVC) ( 28166213) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Pulmonary function ( 21946350) Refractive error ( 32231278) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Schizophrenia ( 28991256) Sleep duration (short sleep) ( 30846698) Subcortical volume (MOSTest) ( 32665545)	Blood protein levels ( 28240269) Hip circumference adjusted for BMI ( 25673412) Refractive error ( 32231278)
Interacting Genes		8 interacting genes: GOLGA6L9 IHO1 LZTS2 MDM4 MEOX2 PDE4DIP SCAND1 TRAF2	54 interacting genes: AGTRAP APH1A CALCOCO2 CCDC51 DGAT2L6 GOLGA6L9 GORASP2 KRT40 LHX4 MAPK3 MAPK8 MZF1 NDUFB5 NFE2 PGBD1 PICK1 PNMA1 POU2AF1 RER1 RNF186 RPRM SFT2D1 SHISA5 SLC17A9 TMEM207 TMEM239 TMEM95 TRIP6 TVP23A ZKSCAN3 ZKSCAN4 ZKSCAN7 ZNF165 ZNF174 ZNF202 ZNF213 ZNF24 ZNF263 ZNF394 ZNF396 ZNF397 ZNF446 ZNF449 ZNF483 ZNF496 ZSCAN12 ZSCAN16 ZSCAN18 ZSCAN20 ZSCAN21 ZSCAN22 ZSCAN23 ZSCAN25 ZSCAN32
Entrez ID		80317	51282
HPRD ID		11705	15298
Ensembl ID		ENSG00000189298	ENSG00000171222
Uniprot IDs		Q9BRR0	H0UIA5 P57086 Q9NZG6
PDB IDs
Enriched GO Terms of Interacting Partners?
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