SLC66A2 and ADH5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		SLC66A2	ADH5
Description		solute carrier family 66 member 2	alcohol dehydrogenase 5 (class III), chi polypeptide
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Trans-Golgi Network Cytosol Integral Component Of Membrane	Mitochondrion Cytosol Extracellular Exosome
	Molecular Function	Protein Binding	Alcohol Dehydrogenase Activity, Zinc-dependent Fatty Acid Binding Zinc Ion Binding Electron Transfer Activity Formaldehyde Dehydrogenase Activity Identical Protein Binding S-(hydroxymethyl)glutathione Dehydrogenase Activity S-(hydroxymethyl)glutathione Dehydrogenase NADP Activity S-(hydroxymethyl)glutathione Dehydrogenase NAD Activity
	Biological Process	Retrograde Transport, Endosome To Golgi Phospholipid Translocation	Retinoid Metabolic Process Respiratory System Process Ethanol Oxidation Fatty Acid Omega-oxidation Peptidyl-cysteine S-nitrosylation Electron Transport Chain Response To Lipopolysaccharide Positive Regulation Of Blood Pressure Formaldehyde Catabolic Process Response To Nitrosative Stress Response To Redox State
Pathways			Ethanol oxidation
Drugs			NADH Lauric acid 12-Hydroxydodecanoic Acid S-Hydroxymethyl Glutathione
Diseases
GWAS			Alcohol consumption ( 28937693) Alcohol consumption in current drinkers ( 28937693) Alcohol dependence ( 23456092) Blood protein levels ( 30072576) HDL cholesterol ( 24097068 25961943) HDL cholesterol levels ( 28334899) Obesity-related traits ( 23251661) Plateletcrit ( 32888494) Regular attendance at a pub or social club ( 29970889)
Interacting Genes		24 interacting genes: ADH5 AQP6 BEST2 CD79A CLCN7 DIABLO FBLN1 FUNDC2 GJA8 GPR152 IL10RA KCNK5 MFSD14B MGLL RHBDD1 SLC10A1 SLC10A6 SLC25A46 SLC35E3 STX12 TMEM31 TMEM44 TMEM80 ZFYVE27	10 interacting genes: APP ARNT CHD3 CSNK2B ESRRA KEAP1 PRDX1 SLC66A2 SNTA1 VTN
Entrez ID		80148	128
HPRD ID		11454	00064
Ensembl ID		ENSG00000122490	ENSG00000197894
Uniprot IDs		Q8N2U9	P11766 Q6IRT1
PDB IDs			1M6H 1M6W 1MA0 1MC5 1MP0 1TEH 2FZE 2FZW 3QJ5
Enriched GO Terms of Interacting Partners?
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