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CCDC33 and PLA2G6
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
86
Data Source:
BioGRID
(two hybrid)
CCDC33
PLA2G6
Description
coiled-coil domain containing 33
phospholipase A2 group VI
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Peroxisome
Extracellular Space
Mitochondrion
Cytosol
Plasma Membrane
Integral Component Of Membrane
Pseudopodium
Centriolar Satellite
Molecular Function
Protein Binding
1-alkyl-2-acetylglycerophosphocholine Esterase Activity
Lysophospholipase Activity
Phospholipase A2 Activity
Protein Binding
Calmodulin Binding
Palmitoyl-CoA Hydrolase Activity
Hydrolase Activity
Serine Hydrolase Activity
Protein Kinase Binding
Identical Protein Binding
ATP-dependent Protein Binding
Calcium-independent Phospholipase A2 Activity
Phosphatidyl Phospholipase B Activity
Myristoyl-CoA Hydrolase Activity
Biological Process
Positive Regulation Of Protein Phosphorylation
Chemotaxis
Positive Regulation Of Cytosolic Calcium Ion Concentration
Memory
Urinary Bladder Smooth Muscle Contraction
Antibacterial Humoral Response
Cardiolipin Biosynthetic Process
Phosphatidylcholine Catabolic Process
Response To Endoplasmic Reticulum Stress
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Cardiolipin Acyl-chain Remodeling
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Vasodilation
Positive Regulation Of Exocytosis
Phosphatidylethanolamine Catabolic Process
Platelet Activating Factor Metabolic Process
Phosphatidic Acid Metabolic Process
Negative Regulation Of Synaptic Transmission, Glutamatergic
Maternal Process Involved In Female Pregnancy
Positive Regulation Of Protein Kinase C Signaling
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Positive Regulation Of Arachidonic Acid Secretion
Regulation Of Store-operated Calcium Channel Activity
Positive Regulation Of Ceramide Biosynthetic Process
Pathways
Acyl chain remodelling of PC
Acyl chain remodeling of CL
Acyl chain remodelling of PE
Role of phospholipids in phagocytosis
COPI-independent Golgi-to-ER retrograde traffic
Drugs
Quinacrine
Diseases
GWAS
Bacterial meningitis (
31092817
)
Coffee consumption (cups per day) (
31837886
)
Craniofacial microsomia (
26853712
)
Diastolic blood pressure (
30224653
)
Diisocyanate-induced asthma (
25918132
)
Hip circumference adjusted for BMI (
34021172
)
Obesity-related traits (
23251661
)
Systolic blood pressure (
30578418
)
Apolipoprotein A1 levels (
32203549
)
Body fat percentage (
26833246
)
Brain morphology (MOSTest) (
32665545
)
Breast cancer (
29059683
)
C-reactive protein levels or triglyceride levels (pleiotropy) (
27286809
)
Cutaneous nevi (
21478494
19578365
)
HDL cholesterol levels (
32203549
)
High light scatter reticulocyte count (
32888494
)
Mammographic density (dense area) (
25342443
)
Melanoma (
21983787
28212542
)
Nevus count (
30429480
)
Nevus count or cutaneous melanoma (
32341527
30429480
)
Percent mammographic density (
25342443
)
Platelet distribution width (
32888494
)
Refractive error (
32231278
)
Reticulocyte count (
32888494
)
Triglyceride levels (
32203549
28334899
32154731
)
Triglycerides (
24097068
20686565
)
Interacting Genes
160 interacting genes:
ABCF3
ABLIM3
ANKS1A
AP1M1
APP
ARHGEF6
ARIH2
ARMC7
ARNT2
BCCIP
BLK
BLZF1
BYSL
C1orf109
CABP2
CALCOCO2
CCDC102B
CCDC57
CCDC6
CCDC85B
CCHCR1
CCNH
CDC23
CDCA7L
CDKN2B
CENPP
CFAP206
CHCHD3
CINP
CIR1
CRYBA2
CRYBA4
CTNNA3
DGCR6
DIP2A
DVL2
DVL3
EAF1
EFEMP2
EHMT2
EMC2
EMD
ESRRG
EXOC8
FAM124A
FAM161A
FAM214B
FRS3
FXR2
GCC1
GPANK1
GPATCH2L
GRN
GYS1
HEXIM2
HGS
HNRNPF
HNRNPK
HOOK2
HOXA1
HSF2BP
IL16
ING5
ITGB1BP1
KANK2
KCTD19
KCTD9
KDM1A
KHDRBS3
KIFC3
KLHL38
KXD1
L3MBTL2
LDOC1
LMO1
LMO2
LMO3
LNX1
MAGED1
MAGOHB
MAPK9
MDFI
MFAP1
MID2
MIPOL1
MISP
MKRN3
MLH1
MOS
NAB2
NCK2
NDOR1
NECAB2
NEFL
NINL
NME7
OSGIN1
OSTF1
PCSK5
PID1
PIK3R3
PIN1
PLA2G6
PLSCR1
PNMA1
PNMA2
POLR1C
PPP2R3C
PRKAA2
PRKAB2
PRPF31
PTGER3
PTK6
QARS1
RAD51D
RAD54B
RBMX
RHOXF2
RNF6
SCNM1
SMAD3
SMARCB1
SMARCD1
SMYD1
SPAG5
SPG21
STK16
STX11
SYT17
TASOR2
TCEANC
TGFB1
TMCC2
TNS2
TRAF2
TRIM23
TRIM37
TRIM42
TRIM59
TSC22D4
TSEN15
TSGA10
TTC19
TUFT1
TXK
TXLNA
UBASH3A
UBQLN4
UNG
USHBP1
VPS52
WT1
YES1
ZBTB8A
ZGPAT
ZNF330
ZNF572
ZNF688
ZNF76
ZNRD2
12 interacting genes:
CACNA1I
CALM1
CCDC33
CEP76
MAT2B
NUP93
RCBTB2
RUSC1
SERTAD2
TRIM50
USP54
ZBTB42
Entrez ID
80125
8398
HPRD ID
09959
04675
Ensembl ID
ENSG00000140481
ENSG00000184381
Uniprot IDs
Q8N5R6
O60733
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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