VCPIP1 and SPRTN

Number of citations of the paper that reports this interaction (PubMedID 32649882)
7

Data Source:
BioGRID (affinity chromatography technology, imaging technique, enzymatic study)

		VCPIP1	SPRTN
Description		valosin containing protein interacting protein 1	SprT-like N-terminal domain
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Lumen Golgi Stack	Chromatin Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Thiol-dependent Deubiquitinase	Double-stranded DNA Binding Single-stranded DNA Binding Metalloendopeptidase Activity Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Mitotic Cell Cycle Cellular Response To DNA Damage Stimulus Endoplasmic Reticulum Membrane Fusion Protein Ubiquitination Protein Deubiquitination Protein K11-linked Deubiquitination Protein K48-linked Deubiquitination Golgi Reassembly Protein-DNA Covalent Cross-linking Repair Regulation Of Protein Localization To Chromatin	Proteolysis Cellular Response To DNA Damage Stimulus Response To UV Protein Autoprocessing Translesion Synthesis Positive Regulation Of Protein Ubiquitination Protein-DNA Covalent Cross-linking Repair
Pathways		Ovarian tumor domain proteases	Translesion Synthesis by POLH
Drugs
Diseases
GWAS			Hematocrit ( 32888494) Hemoglobin ( 32888494)
Interacting Genes		10 interacting genes: FCHSD2 GSK3A SMAD9 SNTG2 SPRTN STX5 UBC VAV2 VCP WAC	4 interacting genes: POLD3 RNF11 UBC VCPIP1
Entrez ID		80124	83932
HPRD ID		15645	13164
Ensembl ID		ENSG00000175073	ENSG00000010072
Uniprot IDs		Q96JH7	A0A024R3U2 Q9H040
PDB IDs			5IY4 6MDW 6MDX
Enriched GO Terms of Interacting Partners?
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