ATF7IP2 and MED4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ATF7IP2	MED4
Description		activating transcription factor 7 interacting protein 2	mediator complex subunit 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Membrane Mediator Complex Core Mediator Complex
	Molecular Function		Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Nuclear Receptor Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process		Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Pathways			PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Copper levels ( 26025379) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Disease progression to choroidal neovascularization form in age-related macular degeneration ( 29346644) Night sleep phenotypes ( 27126917) Response to antipsychotic treatment ( 20195266)	Proportion of activated microglia (inferior temporal cortex) ( 30679421) Thiopurine-induced acute severe leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced early leukopenia in Crohn's disease ( 25108385) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe leukopenia in inflammatory bowel disease ( 29923122)
Interacting Genes		6 interacting genes: FSD2 MBD1 MED4 NUP62 SETDB1 SP1	41 interacting genes: AMOT AP2M1 ATF7IP ATF7IP2 C1orf216 CCDC146 CCHCR1 CTDP1 CTNNBL1 FAM13C FOXJ3 FRMD6 FTCD GCC1 HAUS1 HGS IP6K3 KIFC3 LRRFIP1 MAB21L3 MCRS1 MED30 MED9 NDE1 OIP5 PCBD2 PUM2 SDCBP SDCBP2 SGF29 SMARCD1 SMARCE1 SSX3 SYCE2 TLE5 TNFAIP8 TNFAIP8L1 TXLNA TXLNB USHBP1 WDTC1
Entrez ID		80063	29079
HPRD ID		16517	16145
Ensembl ID		ENSG00000166669	ENSG00000136146
Uniprot IDs		Q5U623	A0A024RDY7 Q9NPJ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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