ERMP1 and MR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ERMP1	MR1
Description		endoplasmic reticulum metallopeptidase 1	major histocompatibility complex, class I-related
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Golgi Membrane Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Early Endosome Membrane Late Endosome Membrane MHC Class I Protein Complex
	Molecular Function	Protein Binding Metalloexopeptidase Activity Metal Ion Binding	Protein Binding Beta-2-microglobulin Binding MHC Class I Receptor Activity T Cell Receptor Binding
	Biological Process	Proteolysis Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Positive Regulation Of T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Immune Response Antigen Processing And Presentation Of Exogenous Antigen T Cell Differentiation In Thymus Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways
Drugs			Antithymocyte immunoglobulin (rabbit)
Diseases
GWAS		Asthma ( 31959851 31619474) Blond vs. brown/black hair color ( 30531825) Waist-hip ratio ( 28552196)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Post bronchodilator FEV1 ( 26634245) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		38 interacting genes: AQP2 AQP6 ATP1B4 BCL2L13 BSCL2 CD200R1 CLDN5 CLDN7 CLDN9 CLEC2D CREB3L1 ERVFRD-1 FAM209A FNDC9 GJA8 GPR42 GPRC5D HHLA2 HIBADH IER3IP1 IFNGR2 KCNN3 KLRC1 LYPD5 MLANA MR1 PDCD1LG2 PEX12 RHCG SLC13A4 SLC22A23 SLC23A2 SLC7A14 SPAG4 SSMEM1 TMEM237 TMEM45A TMEM80	7 interacting genes: CDS2 CXCL9 EMP3 ERMP1 FATE1 GALNT15 NINJ2
Entrez ID		79956	3140
HPRD ID		17227	09012
Ensembl ID		ENSG00000099219	ENSG00000153029
Uniprot IDs		Q6ZMD3 Q7Z2K6	Q95460
PDB IDs			4GUP 4L4T 4L4V 4LCW 4NQC 4NQD 4NQE 4PJ5 4PJ7 4PJ8 4PJ9 4PJA 4PJB 4PJC 4PJD 4PJE 4PJF 4PJG 4PJH 4PJI 4PJX 5D5M 5D7I 5D7J 5D7L 5U16 5U17 5U1R 5U2V 5U6Q 5U72 6MWR 6PUC 6PUD 6PUE 6PUF 6PUG 6PUH 6PUI 6PUJ 6PUK 6PUL 6PUM 6PVC 6PVD 6W9U 6W9V 6XQP
Enriched GO Terms of Interacting Partners?
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