L2HGDH and NIN

		L2HGDH	NIN
Description		L-2-hydroxyglutarate dehydrogenase	ninein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane Integral Component Of Mitochondrial Inner Membrane	Pericentriolar Material Spindle Pole Nucleoplasm Nucleolus Centrosome Centriole Cytoplasmic Microtubule Plasma Membrane Dendrite Axonal Growth Cone Apical Part Of Cell Mitotic Spindle Mitotic Spindle Pole Ciliary Transition Fiber Centriolar Subdistal Appendage
	Molecular Function	(S)-2-hydroxy-acid Oxidase Activity 2-hydroxyglutarate Dehydrogenase Activity	Calcium Ion Binding Protein Binding GTP Binding Kinase Binding Microtubule Minus-end Binding
	Biological Process	2-oxoglutarate Metabolic Process Cellular Protein Metabolic Process	Protein Localization Centriole-centriole Cohesion Corpus Callosum Morphogenesis Corticospinal Tract Morphogenesis Positive Regulation Of Microtubule Polymerization Microtubule Anchoring At Centrosome Collateral Sprouting Positive Regulation Of Axonogenesis Centrosome Localization Centrosome-templated Microtubule Nucleation
Pathways		Interconversion of 2-oxoglutarate and 2-hydroxyglutarate
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163 31015462 31451708) Liver enzyme levels (alanine transaminase) ( 33972514) Periodontal disease-related phenotype (Socransky) ( 24347629) Serum metabolite levels ( 33031748) Systolic blood pressure ( 30224653)	Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 34315874) Asthma (time to childhood onset) x early life tobacco smoke interaction ( 31379025) Cognitive performance ( 20125193) Diastolic blood pressure ( 30578418) Lupus nephritis in systemic lupus erythematosus ( 24925725) Mean platelet volume ( 27863252) Periodontal disease-related phenotype (Socransky) ( 24347629) Pulse pressure ( 30578418) Rectal cancer ( 33632709) Refractive error ( 32231278) Schizophrenia ( 33169155) Stroke ( 32693751) Systolic blood pressure ( 30578418)
Interacting Genes		2 interacting genes: DNAAF2 NIN	21 interacting genes: ABI1 ATL1 AUNIP AURKA BICD1 COCH EIF4ENIF1 GSK3B GTSE1 KLC1 L2HGDH NPTX2 PIAS1 PRKACA RBM10 RTRAF SUMO1 SUN5 TXNDC16 UBE2I YWHAE
Entrez ID		79944	51199
HPRD ID		12640	09785
Ensembl ID		ENSG00000087299	ENSG00000100503
Uniprot IDs		Q9H9P8	Q5XUU0 Q8N4C6
PDB IDs
Enriched GO Terms of Interacting Partners?
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