SEM1 and BRCA2

  • Number of citations of the paper that reports this interaction (PubMedID 12228710)
  • 257
  • Data Source:
  • HPRD (two hybrid, in vivo)

SEM1

BRCA2

Description SEM1 26S proteasome subunit BRCA2 DNA repair associated
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Heel bone mineral density ( 30598549)
  • Liver enzyme levels (alkaline phosphatase) ( 33972514)
  • Serum alkaline phosphatase levels ( 33547301)
Interacting Genes 11 interacting genes: BRCA2 DYNC1I1 MAP1LC3B NUDT21 PCID2 PSMD3 PSMD6 RAD51 RAD52 RPA1 USP14 49 interacting genes: ATM ATR BCCIP BRCA1 BUB1B CCNA1 CCNA2 CCND1 CCNE1 CDK1 CDK2 CFAP52 CHEK1 CHEK2 DMC1 DYNC1LI1 DYNC1LI2 EMSY ERCC5 FANCD2 FANCE FANCG FANCI FLNA H2AX HMG20B HNRNPC KAT2B LIMD1 MAGED1 NEDD4 PALB2 PDS5B PLEC PLK1 RAD51 RNASEH2A RPA1 SEM1 SERPINH1 SMAD3 STAT5A TP53 TP53BP1 UQCC1 USP11 USP21 WTIP XPO1
Entrez ID 7979 675
HPRD ID 03182 02554
Ensembl ID ENSG00000127922 ENSG00000139618
Uniprot IDs P60896 Q6IBB7 P51587
PDB IDs 1IYJ 1MIU 1MJE 3T5X 5GJQ 5GJR 5L4K 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VFR 5VFT 5VGZ 5VHF 5VHH 5VHI 5VHS 6MSB 6MSD 6MSG 6MSH 6MSJ 6MSK 6WJD 6WJN 1N0W 3EU7 6GY2 6HQU
Enriched GO Terms of Interacting Partners?
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