VPS37B and VPS28

Number of citations of the paper that reports this interaction (PubMedID 15218037)
71

Data Source:
HPRD (in vivo)

		VPS37B	VPS28
Description		VPS37B subunit of ESCRT-I	VPS28 subunit of ESCRT-I
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GO Annotations	Cellular Component	ESCRT I Complex Cytoplasm Endosome Plasma Membrane Endosome Membrane Midbody Late Endosome Membrane Extracellular Exosome	ESCRT I Complex Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Late Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Calcium-dependent Protein Binding	Protein Binding Ubiquitin Binding Protein-containing Complex Binding
	Biological Process	Protein Targeting To Membrane Protein Targeting To Vacuole Macroautophagy Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Viral Budding Via Host ESCRT Complex	Macroautophagy Negative Regulation Of Protein Ubiquitination Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Endocytosis
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy	Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Body shape index ( 34021172) Hip circumference adjusted for BMI ( 34021172) Tourette syndrome ( 30818990) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Blood metabolite levels ( 26401656) Educational attainment ( 25201988)
Interacting Genes		25 interacting genes: BAG3 BYSL CDC73 DCUN1D1 ENKD1 ERCC1 EXOC8 FBF1 GORASP2 HGS KDM1A LNX1 NCK2 OSTF1 PRKAA1 PRKAA2 QARS1 SH3YL1 SMARCD1 SORBS3 TLE5 TSG101 UBASH3A UBASH3B VPS28	46 interacting genes: ABI2 ASF1A BEX2 BLZF1 CACNA1I CARD9 CBX5 CCDC146 CDK18 CEP57L1 COX5B FABP3 GABARAP GEM GLCCI1 GOLGA2 INCA1 LMO3 MBIP NRDE2 NXF1 PDCD6IP PNMA5 PRKAA2 PRKAB2 RASSF5 SAXO1 SHC3 SKIL SMN1 SMN2 SUOX TCF12 TCF4 TRIM27 TRIM54 TSG101 TSNAX UBA52 UBC USHBP1 USP2 VPS37A VPS37B VPS37C VPS52
Entrez ID		79720	51160
HPRD ID		07794	11675
Ensembl ID		ENSG00000139722	ENSG00000160948
Uniprot IDs		A0A024RBU0 Q9H9H4	A0A0S2Z5H5 Q548N1 Q9UK41
PDB IDs		6VME	6VME
Enriched GO Terms of Interacting Partners?
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