ZYG11B and NDC1

		ZYG11B	NDC1
Description		zyg-11 family member B, cell cycle regulator	NDC1 transmembrane nucleoporin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cul2-RING Ubiquitin Ligase Complex	Nuclear Envelope Nuclear Pore Cytoplasm Plasma Membrane Actin Cytoskeleton Membrane Integral Component Of Membrane Nuclear Membrane Nuclear Pore Transmembrane Ring
	Molecular Function	Protein Binding	Structural Constituent Of Nuclear Pore Protein-macromolecule Adaptor Activity
	Biological Process	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process	Nucleocytoplasmic Transport Nuclear Pore Organization Homologous Chromosome Pairing At Meiosis Spermatogenesis Protein Transport MRNA Transport Nuclear Pore Complex Assembly Nuclear Pore Localization
Pathways			ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS		Monocyte percentage of white cells ( 32888494)	Response to antidepressants and depression ( 27622933)
Interacting Genes		14 interacting genes: ARPC2 ASPA BTBD2 BTF3L4 CFL2 CUL2 ELOB ELOC GBF1 NDC1 OSBPL9 SH2D2A TLR6 UCK2	4 interacting genes: DNM2 NUP93 UBC ZYG11B
Entrez ID		79699	55706
HPRD ID		13356	08547
Ensembl ID		ENSG00000162378	ENSG00000058804
Uniprot IDs		A8DPD7 B4DK95 Q9C0D3	Q9BTX1
PDB IDs
Enriched GO Terms of Interacting Partners?
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