C3orf52 and TMPRSS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		C3orf52	TMPRSS2
Description		chromosome 3 open reading frame 52	transmembrane serine protease 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Extracellular Region Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding Serine-type Peptidase Activity
	Biological Process		Proteolysis Endocytosis Protein Autoprocessing Positive Regulation Of Viral Entry Into Host Cell
Pathways			Attachment and Entry Attachment and Entry Attachment and Entry
Drugs			Camostat
Diseases
GWAS		Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Prostate cancer ( 25217961)
Interacting Genes		72 interacting genes: ADGRG3 AGER AHNAK2 AMIGO1 AQP6 ATP1B4 BIK CCL21 CCL26 CD33 CHST13 CLDN7 CLEC10A CNMD CPLX4 CREB3 DEXI ERGIC3 ERP29 ESAM FAM209A FFAR2 FNDC9 FOLH1 FUT3 GJA8 GJB1 GOLM2 GORAB HHLA2 HSD17B13 KEL KIR2DL3 KLRC1 LEUTX LHFPL5 LMNA LRRC25 MFF MGST2 MGST3 MRGPRX3 MUC1 NCR3LG1 NEMP1 NPDC1 NSG2 PVR QPCTL REEP3 RNF150 SAR1A SGTA SIGLECL1 SLC10A2 SLC16A2 SLC23A2 SLC39A2 SPRING1 ST6GALNAC3 STOM SYNE4 TIMMDC1 TMEM179B TMEM237 TMEM45B TMEM52B TMEM80 TMPRSS2 TMX2 UPK2 ZNRF3	60 interacting genes: ADIPOQ ANKRD46 AQP1 BMP10 BNIP2 BNIP3 BRICD5 C1QL4 C2CD2L C3orf52 CFHR5 CLEC7A CLK1 CLN6 CMTM7 CNIH2 CNIH3 CTXN3 CXCL9 CYBC1 DEFB103A DEFB103B EDDM3B ERG28 FAM3C FAXDC2 IGFBP5 MOSPD3 NINJ2 PGAP2 PLLP PLN PLP1 PLP2 PTCH1 PTTG1IP SCD SEC22A SELENOK SFTPC SLC35A1 SMIM1 STX7 STX8 TMEM11 TMEM120B TMEM128 TMEM218 TMEM222 TMEM229B TMEM243 TMEM60 TMEM79 TMEM86A TMEM86B TNF TRAPPC10 UPK2 VAMP5 ZFPL1
Entrez ID		79669	7113
HPRD ID		08018	03637
Ensembl ID		ENSG00000114529	ENSG00000184012
Uniprot IDs		Q5BVD1	O15393
PDB IDs
Enriched GO Terms of Interacting Partners?
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