RIC3 and STX7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RIC3	STX7
Description		RIC3 acetylcholine receptor chaperone	syntaxin 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Integral Component Of Membrane Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle Synapse	Immunological Synapse Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Endocytic Vesicle SNARE Complex Early Endosome Membrane Vesicle Azurophil Granule Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome Tertiary Granule
	Molecular Function	Acetylcholine Receptor Binding Protein Folding Chaperone	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity Syntaxin Binding
	Biological Process	Protein Folding Positive Regulation Of Cytosolic Calcium Ion Concentration Synaptic Transmission, Cholinergic Protein Localization To Cell Surface Cellular Protein-containing Complex Assembly Positive Regulation Of Protein Localization To Cell Surface	Positive Regulation Of T Cell Mediated Cytotoxicity Intracellular Protein Transport Vesicle Fusion Vesicle Docking Organelle Localization Organelle Assembly Positive Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Plasma Membrane
Pathways
Drugs		Theophylline
Diseases
GWAS		Blood protein levels ( 30072576) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Malaria ( 31844061)	Body shape index ( 34021172) Cutaneous leishmaniasis ( 32830257) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		16 interacting genes: BCL2L1 CACNA1C CLN6 FA2H FATE1 GOSR2 NINJ2 PRB1 STX12 STX7 TMBIM1 TMEFF2 TMEM11 TMEM86A TRAF3IP3 YIF1A	53 interacting genes: ANKS6 AQP6 ARL13B CERS4 CISD2 CREB3 CREB3L1 CYBRD1 EBP ELOVL5 ENTPD2 FAM174A FAM210B FKBP7 GJC3 HSD17B11 HSD17B13 JAGN1 LIME1 LMNA LSMEM2 MAPK6 MFF MGST3 MRM1 MTUS1 NAPA REEP1 RETREG3 RIC3 SAR1A SLC10A1 SLC10A6 SNAP29 STX1A STX2 STX4 STX6 STX8 TM4SF19 TMEM205 TMEM241 TMEM267 TMEM80 TMPRSS2 TMX2 VAMP7 VAMP8 VPS11 VPS16 VPS18 VTI1B ZFYVE27
Entrez ID		79608	8417
HPRD ID		17974	04449
Ensembl ID		ENSG00000166405	ENSG00000079950
Uniprot IDs		A0A0S2Z607 A0A0S2Z6D3 B7Z3Z0 D3DQU6 Q7Z5B4	O15400
PDB IDs
Enriched GO Terms of Interacting Partners?
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