ZNF557 and NSD3

Number of citations of the paper that reports this interaction (PubMedID 23455924)
46

Data Source:
BioGRID (two hybrid)

		ZNF557	NSD3
Description		zinc finger protein 557	nuclear receptor binding SET domain protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Metal Ion Binding	Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding Histone Methyltransferase Activity (H3-K36 Specific) Transcription Regulator Activator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription, DNA-templated Histone H3-K36 Methylation Histone Methylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Histone H3-K36 Trimethylation
Pathways		Generic Transcription Pathway	PKMTs methylate histone lysines
Drugs
Diseases
GWAS
Interacting Genes		14 interacting genes: CCDC125 CCNDBP1 CEP70 CRK GOLGA6L9 MTUS2 NSD3 PRMT6 SMAD9 SMYD3 STAT3 STX1A SUV39H1 SUV39H2	49 interacting genes: AKT1 AP3M2 ATM BCAR3 BMP8B CASP8 CBLC CBX3 CBX5 CDKN2A CHEK2 DAXX DOCK7 E2F5 ESR1 ETV3 ETV6 FGFR4 GLIS2 GLYR1 H1-1 H3-5 H3C1 H4C1 HOXC4 IVNS1ABP LSM1 MLLT6 MNDA MYC NFIC PAX2 PPM1D RB1CC1 SEPTIN6 SLU7 SOX3 SOX4 SPAG8 SQSTM1 STAC3 TCF3 TEAD2 TERT TGFB1 TRIM55 TRIM63 UBE2I ZNF557
Entrez ID		79230	54904
HPRD ID		15840	06155
Ensembl ID		ENSG00000130544	ENSG00000147548
Uniprot IDs		Q8N988	Q9BZ95
PDB IDs			2DAQ 2NCZ 2ND1 4GND 4GNE 4GNF 4GNG 4RXJ 5UPD 6CEN 6G24 6G25 6G27 6G29 6G2B 6G2C 6G2E 6G2F 6G2O 6G3P 6G3T 7CRP 7CRQ 7CRR
Enriched GO Terms of Interacting Partners?
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