SLC39A7 and STARD3

		SLC39A7	STARD3
Description		solute carrier family 39 member 7	StAR related lipid transfer domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Integral Component Of Membrane	Nucleoplasm Cytoplasm Mitochondrion Lysosomal Membrane Endosome Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Organelle Membrane Contact Site Endoplasmic Reticulum-endosome Membrane Contact Site
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Protein Binding	Protein Binding Cholesterol Binding Protein Homodimerization Activity Cholesterol Transfer Activity
	Biological Process	Cellular Zinc Ion Homeostasis Zinc Ion Transmembrane Transport	Lipid Metabolic Process Progesterone Biosynthetic Process Mitochondrial Transport Steroid Metabolic Process Cholesterol Metabolic Process Cholesterol Transport Vesicle Tethering To Endoplasmic Reticulum Intermembrane Lipid Transfer
Pathways		Zinc influx into cells by the SLC39 gene family	Pregnenolone biosynthesis
Drugs
Diseases
GWAS			Alcohol consumption ( 31358974) Apolipoprotein A1 levels ( 32203549) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) HDL cholesterol ( 24097068 20686565) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Hemoglobin levels ( 32327693) Menopause (age at onset) ( 26414677) Pancreatic ductal adenocarcinoma ( 30541042) Refractive error ( 32231278) Smoking behaviour (cigarettes smoked per day) ( 30679032) Triglyceride levels ( 30108155) Ulcerative colitis ( 20228799)
Interacting Genes		30 interacting genes: AQP6 BIK CLCA4 CRCT1 ERCC6 GJA8 KCNF1 KRTAP1-3 KRTAP5-7 KRTAP9-2 LCE1A LCE1C LCE1F LCE2C LCE2D LCE4A LCE5A LELP1 RGS17 RSPO2 SHISAL1 SLC34A2 SMCP SPRY3 STARD3 TMEM14B TNFRSF10D UNC93A WFDC12 YY1	11 interacting genes: AQP6 CASC3 CLEC11A CREB3 DAPK1 GOPC LMNA MYO1D RNF170 SCGB1A1 SLC39A7
Entrez ID		7922	10948
HPRD ID		09028	06132
Ensembl ID		ENSG00000112473	ENSG00000131748
Uniprot IDs		A0A024RCX7 B4DZZ8 Q92504	Q14849
PDB IDs			1EM2 2I92 5I9J 6TQR 6TQU
Enriched GO Terms of Interacting Partners?
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