C11orf49 and RAB17

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		C11orf49	RAB17
Description		chromosome 11 open reading frame 49	RAB17, member RAS oncogene family
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Endosome Early Endosome Plasma Membrane Endomembrane System Basolateral Plasma Membrane Apical Plasma Membrane Endocytic Vesicle Dendrite Melanosome Neuronal Cell Body Recycling Endosome Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process		Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Intracellular Protein Transport Endocytosis Regulation Of Endocytosis Establishment Of Melanosome Localization Melanosome Transport Endocytic Recycling Transcytosis Filopodium Assembly Regulation Of Dendrite Development Regulation Of Filopodium Assembly Regulation Of Synapse Assembly Cilium Assembly
Pathways			RAB geranylgeranylation
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) D-dimer levels ( 21502573) HDL cholesterol levels ( 32203549) Hip index ( 34021172) Intraocular pressure ( 29617998) Neurociticism ( 29500382)	Obesity-related traits ( 23251661)
Interacting Genes		19 interacting genes: ARHGEF15 CDC16 ENY2 FH GCA GSR PHF1 PNMA5 PRKAR1A PSMA1 RAB17 RAB29 RBM48 RPL8 RPS3A TXN2 UBE3A UBQLN4 ZFHX3	10 interacting genes: ACVR1 BOLA3 C11orf49 FAM9B MAGEA1 NUDT3 RAB7A RABAC1 S100A8 SMURF2
Entrez ID		79096	64284
HPRD ID		08332	11468
Ensembl ID		ENSG00000149179	ENSG00000124839
Uniprot IDs		B4DUV7 Q9H6J7	A0A024R4A4 Q9H0T7
PDB IDs
Enriched GO Terms of Interacting Partners?
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