TMEM109 and AQP9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM109	AQP9
Description		transmembrane protein 109	aquaporin 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Outer Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Membrane Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Molecular_function Voltage-gated Ion Channel Activity Protein Binding	Amine Transmembrane Transporter Activity Purine Nucleobase Transmembrane Transporter Activity Pyrimidine Nucleobase Transmembrane Transporter Activity Water Transmembrane Transporter Activity Protein Binding Polyol Transmembrane Transporter Activity Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Urea Channel Activity Carboxylic Acid Transmembrane Transporter Activity
	Biological Process	Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Cell Death Cellular Response To Gamma Radiation	Water Transport Purine Nucleobase Transport Response To Osmotic Stress Excretion Response To Organic Substance Canalicular Bile Acid Transport Polyol Transport Glycerol Transport Amine Transport Pyrimidine Nucleobase Transport Water Homeostasis Response To Mercury Ion Carboxylic Acid Transport Cellular Response To CAMP Urea Transmembrane Transport Pyrimidine-containing Compound Transmembrane Transport Purine Nucleobase Transmembrane Transport Carboxylic Acid Transmembrane Transport
Pathways			Transport of glycerol from adipocytes to the liver by Aquaporins Passive transport by Aquaporins
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Aspartate aminotransferase levels ( 33547301) Glycine levels ( 30837465) HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels in HIV infection ( 33109212) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Ischemic stroke ( 26089329) LDL cholesterol levels in HIV infection ( 33109212) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Liver enzyme levels (alkaline phosphatase) ( 33972514) Low density lipoprotein cholesterol levels ( 29403010) Metabolite levels ( 23823483 22916037) Serum alkaline phosphatase levels ( 33547301) Small cell lung carcinoma ( 28604730) Stroke ( 26089329) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		16 interacting genes: AQP2 AQP9 ERGIC3 GOLM1 GPX8 LMNA MGST3 MTIF3 PDZK1IP1 RNF170 SAR1A SLC18A2 SPINT1 STOM TMEM52B TMEM80	24 interacting genes: ADAM33 AIG1 APOD CCDC167 CLDN19 CPLX4 CTXN3 CXCL16 EMC6 FATE1 FXYD3 FZD7 GAST HHLA2 IGFBP5 LHFPL5 MIP PAEP SERINC1 SGPL1 SLC38A7 TF TMED9 TMEM109
Entrez ID		79073	366
HPRD ID		14687	04223
Ensembl ID		ENSG00000110108	ENSG00000103569
Uniprot IDs		Q9BVC6	H0YK62 O43315
PDB IDs
Enriched GO Terms of Interacting Partners?
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