PRRG4 and AOC3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		PRRG4	AOC3
Description		proline rich and Gla domain 4	amine oxidase copper containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Cytoplasm Early Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Microvillus Cell Surface Integral Component Of Membrane
	Molecular Function	Molecular_function Calcium Ion Binding Protein Binding WW Domain Binding	Copper Ion Binding Calcium Ion Binding Protein Binding Primary Amine Oxidase Activity Identical Protein Binding Protein Heterodimerization Activity Quinone Binding Tryptamine:oxygen Oxidoreductase (deaminating) Activity Aminoacetone:oxygen Oxidoreductase(deaminating) Activity Aliphatic-amine Oxidase Activity Phenethylamine:oxygen Oxidoreductase (deaminating) Activity
	Biological Process	Biological_process	Inflammatory Response Cell Adhesion Amine Metabolic Process Response To Antibiotic Negative Regulation Of Primary Amine Oxidase Activity
Pathways			Phase I - Functionalization of compounds
Drugs			Phenelzine Hydralazine 6-hydroxydopa quinone
Diseases
GWAS		Parkinson's disease (age of onset) ( 19772629) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		32 interacting genes: ABL2 AOC3 ARHGEF7 BCL10 CYGB ERBB3 ERBB4 FYN GRAP GRB2 HCK HDAC1 HECW1 HLA-C ITCH ITSN1 LYN MAGI1 MAGI2 MAGI3 NEBL NEDD4L OSTF1 PEX13 RBBP8 TEC UBE2K VAV2 VEGFA WWP1 WWTR1 YAP1	13 interacting genes: ARL13B CLDN9 CPLX4 CREB3L1 DARS2 FNDC9 HSD17B13 LMNA MYBPC2 PRRG4 SGTA STX1A VAV1
Entrez ID		79056	8639
HPRD ID		15187	04770
Ensembl ID		ENSG00000135378	ENSG00000131471
Uniprot IDs		A0A0S2Z5N9 Q9BZD6	Q16853 Q9UEU7
PDB IDs			1PU4 1US1 2C10 2C11 2Y73 2Y74 3ALA 4BTW 4BTX 4BTY
Enriched GO Terms of Interacting Partners?
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