NOC4L and DNAJA3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		NOC4L	DNAJA3
Description		nucleolar complex associated 4 homolog	DnaJ heat shock protein family (Hsp40) member A3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Integral Component Of Membrane Noc4p-Nop14p Complex Nuclear Membrane Small-subunit Processome	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Actin Filament Extrinsic Component Of Plasma Membrane Neuromuscular Junction Intracellular Membrane-bounded Organelle Postsynaptic Membrane
	Molecular Function	RNA Binding Protein Binding	Protein Binding ATP Binding Hsp70 Protein Binding GTPase Regulator Activity Metal Ion Binding Unfolded Protein Binding
	Biological Process	RRNA Processing	Negative Regulation Of Transcription By RNA Polymerase II Mitochondrial DNA Replication Protein Folding Activation-induced Cell Death Of T Cells Mitochondrion Organization Small GTPase Mediated Signal Transduction Cell Aging Negative Regulation Of Cell Population Proliferation Response To Heat T Cell Differentiation In Thymus Positive Regulation Of T Cell Proliferation Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Catalytic Activity Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Body mass index ( 26426971) Hirschsprung disease ( 26887379) Response to antidepressants (symptom improvement) ( 29160301) Response to SSRI (symptom remission) ( 29160301)	Erectile dysfunction ( 30583798) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Immature fraction of reticulocytes ( 32888494) Schizophrenia ( 28991256) Triglyceride levels ( 32203549) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		23 interacting genes: BHLHE40 DAZAP2 DNAJA3 DUSP29 EPM2AIP1 IKZF1 KRT15 KRTAP19-6 LINC00839 LNPK NECAB2 NT5C2 OGT OXER1 PICK1 PLSCR1 PRSS23 TSC22D4 UBQLN2 USHBP1 VIM ZBTB42 ZNRD2	48 interacting genes: ATXN1 BRCA1 C2CD6 CACNA1C CARM1 CIDEB COIL CYSRT1 FAM131C FAM214B FBXO7 FOSL2 FRMD6 FXR1 GCC1 GFI1B GRB2 HSPA1A HSPA8 IFNGR2 IFT140 INPP5J JAK2 KDM1A KRAS LAMTOR5 MCPH1 MET MYO15B NFKBIA NFKBIB NOC4L NTRK1 OSGIN1 PRMT6 PTEN RAD51 RASA1 RELA RNF34 SHANK3 SMAD9 SMARCB1 STK16 TCF19 USP7 VHL ZBTB22
Entrez ID		79050	9093
HPRD ID		14543	09758
Ensembl ID		ENSG00000184967	ENSG00000103423
Uniprot IDs		Q9BVI4	B3KM81 Q53G26 Q59E88 Q96EY1
PDB IDs			2CTT 2DN9 6IWS
Enriched GO Terms of Interacting Partners?
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