SLX1B and THAP11

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		SLX1B	THAP11
Description		SLX1 homolog B, structure-specific endonuclease subunit	THAP domain containing 11
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Slx1-Slx4 Complex	Chromatin Nucleoplasm Cytosol
	Molecular Function	Protein Binding Crossover Junction Endodeoxyribonuclease Activity 5'-flap Endonuclease Activity Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Telomere Maintenance Via Telomere Lengthening Telomeric D-loop Disassembly Nucleic Acid Phosphodiester Bond Hydrolysis T-circle Formation Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of T-circle Formation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		Resolution of D-loop Structures through Holliday Junction Intermediates Fanconi Anemia Pathway
Drugs
Diseases
GWAS			Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 27863252) Schizophrenia ( 25056061 29483656)
Interacting Genes		4 interacting genes: DCTPP1 DUSP10 THAP11 TUBA1B	21 interacting genes: BBLN CASP3 CTBP1 ECT2 HCFC1 HDAC1 HDAC3 HEMGN L3MBTL2 LRRC45 MCPH1 NUTF2 OGT PFDN6 PSMC5 SIN3A SLX1B SRSF11 THAP7 TPX2 VPS52
Entrez ID		79008	57215
HPRD ID		14673	11629
Ensembl ID		ENSG00000181625	ENSG00000168286
Uniprot IDs		Q9BQ83	Q96EK4
PDB IDs			2LAU 5AJS
Enriched GO Terms of Interacting Partners?
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