MOGS and MXD1

		MOGS	MXD1
Description		mannosyl-oligosaccharide glucosidase	MAX dimerization protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Exosome	Chromatin Nucleoplasm Mitochondrion Cytosol
	Molecular Function	Mannosyl-oligosaccharide Glucosidase Activity Glucosidase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity
	Biological Process	Protein Folding Protein N-linked Glycosylation Oligosaccharide Metabolic Process Viral Protein Processing	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		Defective MOGS causes MOGS-CDG (CDG-2b) N-glycan trimming in the ER and Calnexin/Calreticulin cycle Maturation of spike protein Maturation of spike protein
Drugs
Diseases
GWAS			Carotid plaque burden (smoking interaction) ( 24954085) High light scatter reticulocyte count ( 32888494 27863252) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494 27863252) Red cell distribution width ( 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		9 interacting genes: C1D CHGB ETAA1 EXOC6B MXD1 PCBP1 RAB11FIP5 REL VPS54	20 interacting genes: AKT1 APP CD2 HDAC1 HDAC2 MAX MLX MOGS MYC MYCL MYCN PML PRAM1 REL RPS6KA1 RPS6KB1 SAP30 SIN3A SIN3B SMC3
Entrez ID		7841	4084
HPRD ID		03214	02487
Ensembl ID		ENSG00000115275	ENSG00000059728
Uniprot IDs		A0A384MDR6 Q13724 Q58F09	B7ZLI7 Q05195
PDB IDs			1E91 1G1E 1NLW 1PD7 1S5Q
Enriched GO Terms of Interacting Partners?
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