ZNF200 and PPARGC1B

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		ZNF200	PPARGC1B
Description		zinc finger protein 200	PPARG coactivator 1 beta
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Mitochondrion Cytosol Mediator Complex
	Molecular Function	Molecular_function Protein Binding Metal Ion Binding	Transcription Coregulator Activity RNA Binding Transcription Factor Binding Estrogen Receptor Binding Nuclear Receptor Coactivator Activity AF-2 Domain Binding
	Biological Process	Biological_process	Ossification Regulation Of Transcription, DNA-templated Mitochondrial Transcription Actin Filament Organization Positive Regulation Of Alkaline Phosphatase Activity Intracellular Estrogen Receptor Signaling Pathway Cellular Response To Reactive Oxygen Species Positive Regulation Of Phosphorylation Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Bone Resorption Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity Response To Glucocorticoid Response To CAMP Bone Trabecula Formation Positive Regulation Of Cold-induced Thermogenesis
Pathways		Generic Transcription Pathway	PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis Regulation of RUNX2 expression and activity Regulation of RUNX2 expression and activity
Drugs			Amiodarone
Diseases
GWAS			Age spots ( 29895819) Apolipoprotein A1 levels ( 32203549) Basal cell carcinoma ( 31174203) Cutaneous malignant melanoma ( 32341527) Deep white matter hyperintensities ( 32517579) Electrocardiographic traits (multivariate) ( 32602732) Facial pigmentation measurement (polar light) ( 32835660) Facial pigmentation measurement (UV light) ( 32835660) Freckles ( 29895819) HDL cholesterol levels ( 32203549) Keratinocyte cancer (MTAG) ( 31174203) Low tan response ( 29739929) Nevus count ( 30429480) Nevus count or cutaneous melanoma ( 30429480) Nontraumatic osteonecrosis of the femoral head ( 32701715) Obesity-related traits ( 23251661) Tanning ( 19340012) Vitiligo ( 27723757)
Interacting Genes		3 interacting genes: FHL2 PPARGC1B SKIL	13 interacting genes: AKT1 ESR1 ESRRG HCFC1 HNF4A PPARA SRC THRB ZBTB9 ZFP64 ZNF200 ZNF212 ZNF513
Entrez ID		7752	133522
HPRD ID		04452	10594
Ensembl ID		ENSG00000010539	ENSG00000155846
Uniprot IDs		B3KP91 P98182	B7ZM40 Q86YN6
PDB IDs			3SP6 6D0Y
Enriched GO Terms of Interacting Partners?
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