CFAP410 and NEK1

Number of citations of the paper that reports this interaction (PubMedID 32891887)
1

Data Source:
BioGRID (enzymatic study)

		CFAP410	NEK1
Description		cilia and flagella associated protein 410	NIMA related kinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Cytoplasm Mitochondrion Cytosol Plasma Membrane Photoreceptor Connecting Cilium Ciliary Basal Body Intracellular Membrane-bounded Organelle	Pericentriolar Material Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Centriolar Satellite
	Molecular Function	Molecular_function Protein Binding	Protein Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding 14-3-3 Protein Binding Protein Serine Kinase Activity
	Biological Process	Cytoskeleton Organization Smoothened Signaling Pathway Regulation Of Cell Shape DNA Damage Response, Detection Of DNA Damage Cilium Assembly	Protein Phosphorylation Cell Cycle Peptidyl-tyrosine Phosphorylation DNA Damage Response, Detection Of DNA Damage Cell Division Cilium Assembly
Pathways
Drugs			Fostamatinib
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Daytime nap ( 33568662) Night sleep phenotypes ( 27126917) Schizophrenia ( 28991256 25056061 29483656) Supramarginal gyrus volume ( 31530798)
Interacting Genes		7 interacting genes: ATOX1 COL6A1 DOP1B FBXO3 GMCL1 NEK1 SPG21	27 interacting genes: ANXA10 ATRX CFAP410 CLCN3 CSN2 CTNNAL1 EXOSC4 FEZ1 FEZ2 GTF2H4 H2BC21 HAND2 HIP1R KIF3A LRRK1 LRRK2 MFHAS1 MRE11 PPP2R5A PTPRD RTN4R SIRPA TAF9 TP53BP1 TSC2 YWHAH ZNF350
Entrez ID		755	4750
HPRD ID		04427	06847
Ensembl ID		ENSG00000160226	ENSG00000137601
Uniprot IDs		O43822	Q5JXL9 Q96PY6
PDB IDs			4APC 4B9D
Enriched GO Terms of Interacting Partners?
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