ZIC3 and DNAI1

		ZIC3	DNAI1
Description		Zic family member 3	dynein axonemal intermediate chain 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Extracellular Region Centrosome Cytoskeleton Microtubule Cilium Outer Dynein Arm 9+2 Motile Cilium
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Cytoskeletal Motor Activity Protein Binding Dynein Light Chain Binding Dynein Heavy Chain Binding
	Biological Process	Heart Looping Regulation Of Transcription By RNA Polymerase II Determination Of Left/right Symmetry Central Nervous System Development Cell Differentiation Lung Development Determination Of Pancreatic Left/right Asymmetry Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Determination Of Digestive Tract Left/right Asymmetry Determination Of Liver Left/right Asymmetry	Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Microtubule-based Movement Determination Of Left/right Symmetry Heart Development Insulin Receptor Signaling Pathway Flagellated Sperm Motility Outer Dynein Arm Assembly
Pathways		POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Anti-drug antibodies in autoimmune disease (time to event) ( 33125391)
Interacting Genes		7 interacting genes: CTNNB1 DNAI1 GLI3 POFUT1 SRF TP53 TWIST1	8 interacting genes: ATG10 CDKN2A EEF1AKMT3 GLDC NPR2 PAFAH1B1 SQSTM1 ZIC3
Entrez ID		7547	27019
HPRD ID		02225	05080
Ensembl ID		ENSG00000156925	ENSG00000122735
Uniprot IDs		O60481	A0A087WWV9 A0A140VJI0 Q9UI46
PDB IDs		2EJ4 2RPC
Enriched GO Terms of Interacting Partners?
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