ZBTB14 and INTS3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		ZBTB14	INTS3
Description		zinc finger and BTB domain containing 14	integrator complex subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome	Nucleus Nucleoplasm Cytoplasm Integrator Complex Site Of Double-strand Break SOSS Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Kidney Development Heart Valve Development Cardiac Septum Development Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Coronary Vasculature Development	DNA Repair Cellular Response To DNA Damage Stimulus Response To Ionizing Radiation SnRNA Processing Mitotic G2/M Transition Checkpoint
Pathways			RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872) Lacunar stroke ( 33773637)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Vegetable consumption ( 33693791)
Interacting Genes		60 interacting genes: AP1M1 AP4B1 ASXL3 ATP5PO ATRIP B4GALT6 BAZ2B BYSL C2orf68 CAPN6 CBX8 CDK16 CDKL3 CEP19 COLEC12 DDX6 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 ITGB7 KAT5 KCNAB3 MAD2L1BP MFAP1 MORF4L2 MRPL11 NAA10 NAA11 PIN1 PLAGL1 PNKP POLR2L PRMT1 PTPN2 RNASEH2B RNPS1 RPA1 RPA2 RPL9 RPS25 RPS7 SCNM1 SDCBP SLC4A1 SNRPB2 SYT16 TCEANC TM9SF1 TRIM55 TSTD2 TXN2 WNT9A ZBTB21 ZCCHC10 ZMAT2	6 interacting genes: APP CTDP1 INTS6 NABP2 SUMO2 ZBTB14
Entrez ID		7541	65123
HPRD ID		03674	08644
Ensembl ID		ENSG00000198081	ENSG00000143624
Uniprot IDs		B2R850 O43829	Q68E01
PDB IDs			4OWT 4OWW 4OWX 6WLG
Enriched GO Terms of Interacting Partners?
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