XPNPEP1 and RHOH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		XPNPEP1	RHOH
Description		X-prolyl aminopeptidase 1	ras homolog family member H
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Immunological Synapse Cytoplasm Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cell Projection
	Molecular Function	Aminopeptidase Activity Manganese Ion Binding Protein Homodimerization Activity Metalloaminopeptidase Activity	GTPase Activity GTPase Inhibitor Activity Protein Binding GTP Binding Kinase Inhibitor Activity Protein Kinase Binding Small GTPase Binding
	Biological Process	Proteolysis Bradykinin Catabolic Process	Regulation Of Transcription, DNA-templated Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Motor Neuron Axon Guidance Regulation Of Cell Shape Rac Protein Signal Transduction Cell Projection Assembly T Cell Differentiation Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Catalytic Activity Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Engulfment Of Apoptotic Cell Mast Cell Activation Positive Regulation Of T Cell Differentiation Regulation Of Neutrophil Migration
Pathways			RHOH GTPase cycle
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Biliary atresia ( 20460270) Bipolar disorder ( 31043756 28072414) Refractive error ( 32231278)	Graves' disease ( 21841780) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		13 interacting genes: ANK3 DISC1 GORASP2 GSK3B HBG2 MAPK9 NUDT3 POLA2 RHOH RINT1 SUMO2 UBC UBE2D3	24 interacting genes: ARHGDIA ARHGDIB ARHGDIG BANP CCNH FAM90A1 GDI1 IQUB ITGB1BP1 KANK2 KCNH2 LRIF1 MBLAC1 MTX2 PLEKHA7 RIPPLY1 SCNM1 SORL1 SUOX TCF19 TGFBR1 TMEM33 UTP14A XPNPEP1
Entrez ID		7511	399
HPRD ID		03899	03616
Ensembl ID		ENSG00000108039	ENSG00000168421
Uniprot IDs		Q5T6H7 Q9NQW7	Q15669 Q6ICP4
PDB IDs		3CTZ
Enriched GO Terms of Interacting Partners?
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