DAGLA and MAL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DAGLA	MAL
Description		diacylglycerol lipase alpha	mal, T cell differentiation protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Early Endosome Membrane Dendrite Membrane Dendritic Spine Membrane Varicosity Postsynaptic Membrane Postsynaptic Density Membrane Integral Component Of Postsynaptic Membrane	Endoplasmic Reticulum Integral Component Of Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Membrane Raft
	Molecular Function	Protein Binding Metal Ion Binding Acylglycerol Lipase Activity	Protein Binding Lipid Binding Peptidase Activator Activity Involved In Apoptotic Process Structural Constituent Of Myelin Sheath
	Biological Process	G Protein-coupled Glutamate Receptor Signaling Pathway Neuroblast Proliferation Arachidonic Acid Metabolic Process Neurogenesis Neurotransmitter Biosynthetic Process Diacylglycerol Catabolic Process Endocannabinoid Signaling Pathway Retrograde Trans-synaptic Signaling By Endocannabinoid Regulation Of Neuroinflammatory Response	Membrane Raft Polarization Apoptotic Process Central Nervous System Development Cell Differentiation Myelination Apical Protein Localization
Pathways		Arachidonate production from DAG
Drugs
Diseases
GWAS		Bipolar disorder ( 28115744 31043756) Fasting plasma glucose ( 32902719) Immune reponse to smallpox (secreted IL-2) ( 22610502) Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Red blood cell fatty acid levels ( 25500335) Refractive error ( 32231278)
Interacting Genes		11 interacting genes: CMTM7 LHFPL5 MAL MALL MS4A13 STOM TIMM10 TMEM218 TRARG1 UPK1B VMA21	81 interacting genes: AMHR2 AQP6 BCL2L13 BTN2A1 CALN1 CD300LG CD3G CD40 CD53 CD69 CLDN14 CLDN20 CLDN7 CLDN9 CLEC4C CLSTN3 CPLX4 CREB3L1 CXADR DAGLA EDA EMP1 EVI2A FAM209A FCRL2 FIBCD1 FNDC9 GJA8 GJB1 GPR152 GRAMD1A GSG1L HIBADH IL10RA IL20RB JAML KCNA1 KCNA10 KCNMB4 KLRC1 LDLRAD1 LMAN2L LMNA LRRC25 LRTM1 LSMEM1 MC4R MS4A4A MYD88 NCAPH2 NKAIN4 NPDC1 OPRM1 PERP PLA2G10 PRRT1 PTPRN RAMP1 SDC4 SGCB SHISA3 SHISA4 SLC10A1 SLC35C2 SMIM3 SPINT1 STX1A SYNDIG1 TEX29 TIGIT TM4SF18 TMEM106C TMEM174 TMEM207 TMEM213 TMEM248 TMEM30A TMEM52B TNFSF14 TSPO2 USP7
Entrez ID		747	4118
HPRD ID		07092	01789
Ensembl ID		ENSG00000134780	ENSG00000172005
Uniprot IDs		Q9Y4D2	A0A024RE19 P21145
PDB IDs
Enriched GO Terms of Interacting Partners?
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