VEGFB and FOSL1

		VEGFB	FOSL1
Description		vascular endothelial growth factor B	FOS like 1, AP-1 transcription factor subunit
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane Platelet Alpha Granule Lumen	Chromatin Nucleus Nucleoplasm Cytosol Presynaptic Membrane Neuron Projection
	Molecular Function	Vascular Endothelial Growth Factor Receptor Binding Protein Binding Growth Factor Activity Heparin Binding Chemoattractant Activity Identical Protein Binding Vascular Endothelial Growth Factor Receptor 1 Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Response To Hypoxia Positive Regulation Of Protein Phosphorylation Positive Regulation Of Endothelial Cell Proliferation Sprouting Angiogenesis Protein O-linked Glycosylation Response To Xenobiotic Stimulus Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Angiogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Chemotaxis Induction Of Positive Chemotaxis Positive Regulation Of Cell Division Cardiac Muscle Contraction Positive Regulation Of Mast Cell Chemotaxis Coronary Vasculature Development	In Utero Embryonic Development Regulation Of Transcription By RNA Polymerase II Chemotaxis Cellular Defense Response Vitellogenesis Female Pregnancy Learning Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Response To Xenobiotic Stimulus Response To Mechanical Stimulus Response To Virus Response To Gravity Cellular Response To Extracellular Stimulus Response To Progesterone Response To Cytokine Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Positive Regulation Of Cell Cycle Positive Regulation Of DNA-binding Transcription Factor Activity Response To Corticosterone Response To CAMP Placenta Blood Vessel Development Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription, Initiation
Pathways		Platelet degranulation VEGF ligand-receptor interactions VEGF binds to VEGFR leading to receptor dimerization	NGF-stimulated transcription NGF-stimulated transcription
Drugs		Aflibercept
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Body shape index ( 34021172) Crohn's disease ( 28067908) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Fruit consumption ( 32066663) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Red blood cell count ( 32888494) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for body mass index ( 25673412)	Acne (severe) ( 24927181) Asthma ( 31959851) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 23128233) Psoriasis ( 28537254) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		11 interacting genes: ADRB2 FLT1 FOSL1 KLHL12 NRP1 SF1 TFB1M TNXB UCP2 UCP3 VEGFA	31 interacting genes: ATF2 ATF3 ATF4 ATXN1 BATF3 CALCOCO1 CCDC120 CEBPA CEBPE CEBPG CREB5 DDIT3 DNMT3L EP300 ERCC6 GCC1 JUN JUNB KIFC3 KPNA1 LDOC1 MAF MAFB NME7 PARVG PIN1 TAB2 TRIM24 USF1 VEGFB WFDC1
Entrez ID		7423	8061
HPRD ID		03237	00643
Ensembl ID		ENSG00000173511	ENSG00000175592
Uniprot IDs		P49765 Q7LAP4	A0A0S2Z595 E9PKL5 E9PPX2 P15407
PDB IDs		2C7W 2VWE 2XAC
Enriched GO Terms of Interacting Partners?
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