USF2 and TEAD2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		USF2	TEAD2
Description		upstream transcription factor 2, c-fos interacting	TEA domain transcription factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytosol Intracellular Membrane-bounded Organelle TEAD-YAP Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein Heterodimerization Activity Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Binding DNA-binding Transcription Factor Activity Protein Binding Disordered Domain Specific Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription By RNA Polymerase II Lactation Late Viral Transcription Positive Regulation Of Transcription By RNA Polymerase II Lipid Homeostasis	Vasculogenesis Neural Tube Closure Embryonic Heart Tube Morphogenesis Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Notochord Development Hippo Signaling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Paraxial Mesoderm Development Lateral Mesoderm Development Embryonic Organ Development Negative Regulation Of Cell Death Protein-containing Complex Assembly Cellular Response To Retinoic Acid Regulation Of Stem Cell Differentiation
Pathways		Estrogen-dependent gene expression	YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		11 interacting genes: BRCA1 EP300 FOS ICAM3 LZTS2 MAF NFYA PPARGC1A RELA TEAD2 USF1	45 interacting genes: AKT1 ARNT AURKA BCL2L15 BECN1 C14orf39 CCND2 CDK4 CDK6 CDKN2A CDKN2B DACH1 EPHA2 FGFR4 FZR1 GLIS1 GLIS2 GNG13 HGF HIF1A INPP5A LATS2 MAP2K3 MAP2K5 MAP3K5 MYC NCOA1 NEDD4 NFIC NSD3 RAF1 RASSF1 RUNX1 SAA2 SOX3 STK11 TERT TP53 TRIM3 USF2 VGLL1 VGLL3 VGLL4 WWTR1 YAP1
Entrez ID		7392	8463
HPRD ID		02668	03432
Ensembl ID		ENSG00000105698	ENSG00000074219
Uniprot IDs		Q15853	A0A024QZE2 Q15562
PDB IDs			3L15 5DQ8 5DQE 5EMV 5HGU 6CDY 6E5G 6S60 6S64 6S66 6S69 6S6J 6UYB 6UYC 6VAH
Enriched GO Terms of Interacting Partners?
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