UQCRFS1 and HTR6

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		UQCRFS1	HTR6
Description		ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	5-hydroxytryptamine receptor 6
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Mitochondrial Respiratory Chain Complex IV	Plasma Membrane Integral Component Of Plasma Membrane Cilium Dendrite Synapse
	Molecular Function	Protein Binding Ubiquinol-cytochrome-c Reductase Activity Oxidoreductase Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding	Histamine Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity
	Biological Process	Respiratory Electron Transport Chain Mitochondrial Respiratory Chain Complex III Assembly Proton Transmembrane Transport	G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Cerebral Cortex Cell Migration Positive Regulation Of TOR Signaling G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways		Respiratory electron transport	Serotonin receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin 5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2	Ziprasidone Amitriptyline Olanzapine Clozapine Loxapine Imipramine Chlorpromazine Haloperidol Amoxapine Paroxetine Cyclobenzaprine Ergoloid mesylate Doxepin Quetiapine Aripiprazole Chlorprothixene Dimethyltryptamine Lysergic acid diethylamide Iloperidone SGS518 PRX-07034 SUVN-502 Sertindole Mianserin Asenapine Zotepine Setiptiline Dihydroergocornine Gilteritinib Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases
GWAS		Disease progression in age-related macular degeneration ( 29346644) Methadone dose in opioid dependence ( 28115739) Stroke ( 32693751)	Chronotype ( 26955885 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 27494321)
Interacting Genes		4 interacting genes: CYC1 HTR6 RELB SOX5	32 interacting genes: ABCA2 ACTB AIP AKR1A1 AP2M1 AP4S1 ATXN10 CD160 CHN1 CMSS1 COPS5 DDRGK1 DHRS1 EIF4A3 FYN GNAQ GNAS HDGFL2 IDS MAP1B NF1 NRXN3 PARP8 RUNDC3A SCHIP1 SLC6A1 SRRT SYT5 THY1 TMEM98 TTYH1 UQCRFS1
Entrez ID		7386	3362
HPRD ID		01874	03066
Ensembl ID		ENSG00000169021	ENSG00000158748
Uniprot IDs		P47985	P50406
PDB IDs		5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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