UMOD and MMP8

  • Number of citations of the paper that reports this interaction (PubMedID 8397318)
  • 11
  • Data Source:
  • HPRD (in vitro)

UMOD

MMP8

Description uromodulin matrix metallopeptidase 8
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic kidney disease ( 29124443 26831199 20383146)
  • Chronic kidney disease and serum creatinine levels ( 20686651)
  • Chronic kidney disease x type 2 diabetes interaction ( 32541925)
  • Creatinine levels ( 29124443)
  • Diastolic blood pressure ( 27841878)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (1df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Estimated glomerular filtration rate ( 31015462 29124443 30604766)
  • Estimated glomerular filtration rate (creatinine, CKDi25) ( 33137338)
  • Estimated glomerular filtration rate (creatinine, Rapid3) ( 33137338)
  • Femoral neck bone geometry ( 22087292)
  • Glomerular filtration rate ( 27588450)
  • Glomerular filtration rate (creatinine) ( 28452372 26831199)
  • Glomerular filtration rate (cystatin C) ( 28452372)
  • Glomerular filtration rate in diabetes ( 29703844)
  • Glomerular filtration rate in diabetics (creatinine) ( 26831199)
  • Glomerular filtration rate in non diabetics (creatinine) ( 26831199)
  • Glomerular filtration rate in type 2 diabetes ( 29703844)
  • Hypertension ( 27618447 21082022)
  • Hyperuricemia ( 29124443)
  • Kidney function decline traits ( 25493955)
  • Kidney stones ( 31729369)
  • Medication use (calcium channel blockers) ( 31015401)
  • Renal function and chronic kidney disease ( 19430482)
  • Renal function-related traits (eGRFcrea) ( 22797727)
  • Renal function-related traits (sCR) ( 22797727)
  • Serum uric acid levels ( 29124443)
  • Type 1 diabetes ( 34127860)
  • Urate levels ( 31578528)
  • Urinary uromodulin levels ( 24578125)
Interacting Genes 3 interacting genes: LINC02582 LTA MMP8 7 interacting genes: ACAN BCAN CCL2 FBXO7 TFPI TIMP2 UMOD
Entrez ID 7369 4317
HPRD ID 11771 00385
Ensembl ID ENSG00000169344 ENSG00000118113
Uniprot IDs P07911 B4E0I2 P22894
PDB IDs 4WRN 6TQK 6TQL 6ZS5 6ZYA 1A85 1A86 1BZS 1I73 1I76 1JAN 1JAO 1JAP 1JAQ 1JH1 1JJ9 1KBC 1MMB 1MNC 1ZP5 1ZS0 1ZVX 2OY2 2OY4 3DNG 3DPE 3DPF 3TT4 4QKZ 5H8X
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?