UCHL3 and NSG2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		UCHL3	NSG2
Description		ubiquitin C-terminal hydrolase L3	neuronal vesicle trafficking associated 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Endosome Early Endosome Late Endosome Golgi Apparatus Integral Component Of Membrane Dendrite Cytoplasmic Vesicle Membrane Early Endosome Membrane Multivesicular Body Membrane Trans-Golgi Network Membrane Lysosomal Lumen Golgi Cis Cisterna Membrane
	Molecular Function	Thiol-dependent Deubiquitinase Protein Binding Peptidase Activity NEDD8-specific Protease Activity Ubiquitin Binding	Protein Binding Clathrin Light Chain Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Deubiquitination Protein Catabolic Process Post-translational Protein Modification	Dopamine Receptor Signaling Pathway Endosomal Transport Clathrin Coat Assembly
Pathways		UCH proteinases Synthesis of active ubiquitin: roles of E1 and E2 enzymes Neddylation
Drugs
Diseases
GWAS		Diabetic retinopathy ( 23562823) Metabolite levels ( 23823483)	Alzheimer's disease ( 33074286) Blond vs. brown/black hair color ( 30531825) Diffusing capacity of carbon monoxide ( 30694715) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		22 interacting genes: ATM ATXN7L3 CDH1 FOXM1 LONRF1 NEDD8 NSG2 PJA1 PKD2 PLA2G2A POGK RAD51 TRIM27 TRIM54 TRIM55 TRIM63 UBC UBE2S USP15 USP21 USP28 XRCC5	17 interacting genes: ANKRD46 APOC1 C3orf52 CLEC7A HCFC1R1 NDUFA2 RIF1 RPS27 RRH SERPINH1 SLC35F6 STX18 SUPT4H1 TNNT1 TSPAN6 UCHL3 ZNF768
Entrez ID		7347	51617
HPRD ID		04367	13664
Ensembl ID		ENSG00000118939	ENSG00000170091
Uniprot IDs		A0A087WTB8 A0A140VJZ4 P15374	Q9Y328
PDB IDs		1UCH 1XD3 6ISU 6QML
Enriched GO Terms of Interacting Partners?
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