UBE2I and SMAD4

  • Number of citations of the paper that reports this interaction (PubMedID 15231748)
  • 99
  • Data Source:
  • HPRD (in vitro, two hybrid, in vivo)

UBE2I

SMAD4

Description ubiquitin conjugating enzyme E2 I SMAD family member 4
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 474 interacting genes: - ACTB ADAR ADARB1 ADD3 AGR2 AGTRAP AKAP17A ANAPC4 ANXA1 APEX1 APP AR ARHGDIA ARL13B ARL6IP1 ARNT ARNTL ATF2 ATF3 ATF7IP ATXN1 AURKA AURKB BANP BCAM BCL11A BCL2L1 BEND5 BHLHE40 BIRC3 BIRC7 BLM BLMH BMI1 BTBD3 C18orf25 CALU CAMK2D CAMK2G CAMSAP2 CARD9 CARM1 CASP2 CASP8AP2 CBLC CBS CBX4 CCDC6 CD2AP CDC37 CDCA8 CDH4 CDKN1B CDR2L CEBPD CEBPE CENPX CFL2 CFTR CHD3 CHD4 CHFR CHMP1A CHMP4B CHUK CLDN2 CLK2 COG1 CORO2A CREB1 CREBBP CREBL2 CREM CSGALNACT2 CSK CSNK2B CTBP2 CTNNA1 CYP4F2 DACH1 DAXX DCTD DDX21 DDX24 DDX39A DDX39B DDX5 DES DHX9 DMC1 DNM1 DNMT3A DNMT3B DPPA2 DPYSL2 DRG1 DTX3L DZIP3 EDARADD EDF1 EGR2 EIF2AK2 EIF2B1 ELK1 EP300 ERCC6 ESR1 ETS1 ETV1 ETV6 EXO1 EXOSC9 FADD FAF1 FAM118A FANCM FAS FATE1 FHIT FHL3 FLI1 FMR1 FOS FOXL2 FOXM1 GCM1 GIPC2 GLUL GMCL1 GMCL2 GMEB1 GMEB2 GOLGA1 GOLGA2 GOLGB1 GRIP1 GTF2I H4-16 HABP4 HDAC1 HDAC4 HDAC5 HDAC7 HGS HIC1 HIF1A HIPK1 HIPK2 HIPK3 HIRA HMBOX1 HMGB1 HMGN2 HMGXB4 HNF4A HNRNPC HNRNPCL1 HNRNPD HNRNPK HNRNPLL HNRNPM HNRNPU HSF1 HSF2 HSF2BP IKBKG IKZF1 IKZF3 IKZF5 IMPDH1 IPO13 IQGAP1 JUN JUNB KAT2A KAT6B KCNA5 KCNK1 KCTD1 KDM1A KHSRP KLF3 KLF5 KLHL12 KLHL2 KMT5A KRT19 KRTAP5-2 KRTAP5-4 KRTAP5-9 KTN1 LATS1 LCE1D LCE1F LCE2C LCE3B LCE5A LMNA LMNB1 LMO2 LNX2 LONRF1 LRSAM1 MALL MAP2K1 MAP3K1 MAP3K5 MAPK1IP1L MARCHF5 MAT2A MATR3 MDM2 MECOM MED7 MEF2C MGRN1 MIPOL1 MITF MKRN3 MLX MRTFA MTA1 MYB MYBBP1A MYH9 NACC1 NAF1 NAT10 NCOR2 NFKBIA NIN NMI NOL6 NONO NOP2 NOP56 NOP58 NOX5 NR1D2 NR1H2 NR1H3 NR1I2 NR3C1 NR3C2 NR5A1 NR5A2 NSD3 NUDCD3 NVL PAICS PARK7 PARP1 PAX5 PCNA PDLIM7 PDPK1 PDZK1 PELI1 PEX10 PHC1 PIAS1 PIAS2 PIAS3 PIAS4 PIM1 PLAAT4 PLAGL1 PML POLR1H POU1F1 POU2F1 PPARA PPARG PPARGC1A PPCDC PPM1J PRKAA2 PRKDC PROP1 PRPF40A PRPF8 PRPSAP1 PSMC3 PSMC6 PSME3 PTEN PUF60 RABAC1 RAD18 RAD51 RAD52 RAD54B RAD54L2 RANBP2 RANGAP1 RB1 RBBP5 RBBP6 RBM14 RBM25 RC3H2 RCBTB2 RFPL3 RHOXF2 RIPK2 RNF10 RNF111 RNF115 RNF128 RNF133 RNF144B RNF151 RNF185 RNF4 RNF40 RORB RPL11 RPL7 RPL8 RPRD1B RPS3A RPS6KA6 RUSF1 RWDD3 RXRA SAE1 SALL1 SART1 SATB1 SCNN1A SEMA6A SEPTIN1 SETBP1 SETDB1 SETX SFPQ SH3KBP1 SIAH1 SIAH2 SIRT1 SKIL SLC2A1 SLC2A4 SLX4 SMAD4 SNAI2 SND1 SNIP1 SNRNP200 SOCS6 SOX10 SOX4 SOX5 SOX6 SOX9 SP100 SP3 SPECC1L SPOP SREBF1 SREBF2 SRF SRSF4 SSRP1 STAT1 STMN2 STX1A STX1B STX2 SUMO1 SUMO1P1 SUMO2 SUMO3 SUPT7L SUZ12 SYMPK TAB2 TAF1 TAF10 TAF12 TAF5 TBL1X TBL1XR1 TBP TCERG1 TCF3 TCF4 TDG TDP2 TERF2 TFAP2A TFAP2B TFAP2C TFCP2 TFG THAP1 THRA THRB TIGD3 TLK2 TNFRSF1A TOP1 TOP2A TOP2B TOPORS TP53 TP63 TP73 TRAF2 TRAF3 TRAF4 TRAF6 TRIM21 TRIM23 TRIM24 TRIM27 TRIM28 TRIM29 TRIM3 TRIM38 TRIM41 TRIM54 TRIM63 TRIM72 TRIP13 TRPS1 TSHZ2 TSN TSNAX TTN TXLNB UBA2 UBE2K UBQLN1 UBQLN2 UBXN1 UCHL1 UNC119 USP25 VENTX VEZF1 VHL WNK1 WT1 WWP2 XBP1 XIAP XRCC1 XRCC5 ZBED1 ZBTB1 ZBTB16 ZBTB2 ZBTB26 ZBTB7A ZBTB8A ZBTB9 ZC3H10 ZCCHC12 ZCCHC7 ZEB2 ZG16 ZIC1 ZMYM2 ZNF106 ZNF24 ZNF408 ZNF446 ZNF451 ZNF618 ZNF646 ZNF837 ZNRD2 214 interacting genes: ACVR1B AKT1 ALDOB AOPEP AP2B1 APBB2 AR ARFRP1 ARL5B ATF2 ATF7IP BAAT BCAS3 BEX1 BRCA1 BTRC CAMK2G CCDC180 CD59 CDC14B CEBPA CEBPB CEBPD CHEK1 CITED1 CNKSR1 COPS5 CREBBP CSH1 CSH2 CTCF CTNNB1 CYFIP2 DACH1 DCP1A DCP1B DKK3 DLX1 DNAJB2 DNMT3L DVL1 ECSIT EEF1A1 EID2 EIF2AK4 EP300 ERBIN ESR1 ESR2 ETV4 EWSR1 FANCC FBLN1 FBP2 FBXO30 FBXO34 FHL2 FHL3 FN1 FOXG1 FOXH1 FOXO1 FOXO3 FOXO4 FSTL3 GATA2 GLI3 GPNMB GREB1 HDGF HDLBP HEMGN HMG20A HNF4A HOXA9 HOXC8 HRAS HYAL2 IL24 ITK JUN JUNB JUND LAMTOR5 LEF1 LMO4 LRATD2 LYPD3 MAPK1 MAPK13 MAX MDM4 MECOM MEF2A MEX3B MSANTD3 MYOD1 NAT8 NEK6 NELFCD NFIA NFKBID NKX3-2 NOTCH4 NR0B2 NRAS NUAK2 NUP214 OTUB1 PAK1 PAPPA2 PARD3 PBK PIAS1 PIAS2 PIAS3 PIAS4 PLG PLK4 PPP2CB PPP3R2 PRKAR1B PRKAR2A PRPF40A PSG2 PSG9 PSMD11 RAB13 RAB25 RAB2B RAB34 RAB38 RAB3B RAC2 RALA RASD2 RASL12 RASSF5 RBL1 RELA RFX1 RHEBL1 RHOD RHOG RHOJ RIPK2 RMND5B RPL28 RPS27A RRAS2 RSPH14 S100A14 SASH3 SERPINA1 SERPINB5 SFRP2 SFRP4 SHC1 SKI SKIL SKP2 SMAD1 SMAD2 SMAD3 SMAD5 SMAD7 SMAD9 SNIP1 SNRNP70 SNW1 SOX12 SP1 SPTBN1 SQSTM1 STK11IP STK35 STUB1 STX17 TCTA TDG TENM3 TFE3 TGFBR1 TGFBR2 TGFBRAP1 THRSP TIAF1 TLE5 TM9SF2 TOB1 TRAP1 TSSK3 TSTD2 UBA52 UBB UBE2I UBE2L3 UBE2Z UHRF2 USB1 USP10 USP4 USP9X WWOX XPO5 ZBED5 ZBTB7A ZIC1 ZMYM2 ZNF189 ZNF423 ZNF510 ZNF521 ZNF8
Entrez ID 7329 4089
HPRD ID 09045 02995
Ensembl ID ENSG00000103275 ENSG00000141646
Uniprot IDs A8K503 B0QYN7 P63279 A0A024R274 Q13485
PDB IDs 1A3S 1KPS 1Z5Q 1Z5S 2GRN 2GRO 2GRP 2GRQ 2GRR 2O25 2PE6 2PX9 2XWU 3A4S 3UIN 3UIO 3UIP 4W5V 4Y1L 5D2M 5F6D 5F6E 5F6U 5F6V 5F6W 5F6X 5F6Y 5FQ2 6SYF 1DD1 1G88 1MR1 1U7F 1U7V 1YGS 5C4V 5MEY 5MEZ 5MF0 5UWU
Enriched GO Terms of Interacting Partners?
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