UBA1 and TSSC4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		UBA1	TSSC4
Description		ubiquitin like modifier activating enzyme 1	tumor suppressing subtransferable candidate 4
Image			No pdb structure
GO Annotations	Cellular Component	Heterochromatin Nucleus Nucleoplasm Cytoplasm Mitochondrion Lysosomal Membrane Cytosol Endosome Membrane Desmosome Rough Endoplasmic Reticulum Membrane Extracellular Exosome
	Molecular Function	RNA Binding Ubiquitin Activating Enzyme Activity Protein Binding ATP Binding	Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Protein Ubiquitination Protein Modification By Small Protein Conjugation
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Hexatantalum Dodecabromide Quercetin
Diseases
GWAS			Malaria ( 31844061)
Interacting Genes		52 interacting genes: ABCF1 BUB3 CDC34 CDK1 CHEK1 ECHS1 GAN GRB2 HGS HSPH1 LINC01554 MGMT MTNR1A OGT PIAS3 SEMA3F SMAD5 SUMO2 TAF9 TMCC2 TSSC4 TTC19 UBC UBE2A UBE2B UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2G1 UBE2G2 UBE2H UBE2J1 UBE2J2 UBE2K UBE2L1 UBE2L3 UBE2L6 UBE2M UBE2N UBE2Q2 UBE2R2 UBE2S UBE2T UBE2U UBE2W UBE2Z UBTD2	14 interacting genes: APP CEP76 GMCL1 GOLGA2 KPNA3 REL RNF31 SPTAN1 TAB1 TCF4 TERF2IP TRAF1 TRAF2 UBA1
Entrez ID		7317	10078
HPRD ID		02440	10357
Ensembl ID		ENSG00000130985	ENSG00000184281
Uniprot IDs		A0A024R1A3 P22314	Q9Y5U2
PDB IDs		4P22 6DC6
Enriched GO Terms of Interacting Partners?
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