PRR20E and TRIM35

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PRR20E	TRIM35
Description		proline rich 20E	tripartite motif containing 35
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm
	Molecular Function	Protein Binding	Molecular_function Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process		Apoptotic Process Protein Ubiquitination Positive Regulation Of Apoptotic Process Innate Immune Response Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Viral Release From Host Cell
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS		Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)	Chronotype ( 30696823) Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Lung cancer ( 28604730)
Interacting Genes		89 interacting genes: ABI2 ANKHD1 ARID5A ATXN1 BANP BEND2 BHLHE40 BICRAL C10orf55 C1orf94 C3orf36 CABP2 CCNK CDC37 CELF4 DAZAP2 DMRT3 DVL3 EIF4ENIF1 ESRP1 FAM168A FAM222B FAM9A FOXH1 FOXP3 GLIS2 GTF2A1 HIVEP1 HLX HYPK KRTAP19-1 KRTAP19-5 LASP1 MAGED1 MBNL3 NCK2 NFYC NOTCH3 NTAQ1 OXER1 PATZ1 PHF1 PITX1 POGZ POU2F1 POU6F2 PRR20A PRR20B PRR20C PRR20D PRR34 PRR35 PTTG2 RBM23 RBM42 RBPMS RBPMS2 RHOXF2 RIPPLY1 RNF4 ROR2 SAMD11 SH3RF1 SIAH1 SMAP1 SNRPB SNRPC SP4 SRPK2 TBX3 TBX6 TCF7L2 TFG THAP1 TIAL1 TLX3 TOLLIP TPRX1 TRIM35 VAC14 VENTX VEZF1 VPS37C YPEL3 ZBTB32 ZC3H10 ZCCHC14 ZNF385C ZNF683	49 interacting genes: ADIPOQ BANP CABP2 COL8A1 DTX2 ENKD1 FNDC3B GNMT HNRNPA2B1 IGFN1 KANK2 LCK LMO1 MGAT5B NRF1 PAN2 PARD6B PDCD5 PHF24 PKM PPP2CA PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E QARS1 SHC3 SMARCB1 TCEANC TRAPPC6A TRIM10 TRIM11 TRIM5 TRIM55 TRIM63 TSG101 TSSK3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2U UBE2W USP2 USP49 ZNF410
Entrez ID		729250	23087
HPRD ID		19671	15553
Ensembl ID		ENSG00000234278	ENSG00000104228
Uniprot IDs		P86478 P86479 P86480 P86481 P86496	E5RGB3 Q9UPQ4
PDB IDs
Enriched GO Terms of Interacting Partners?
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