DNLZ and HSPA9

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, pull down)

		DNLZ	HSPA9
Description		DNL-type zinc finger	heat shock protein family A (Hsp70) member 9
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion	SAM Complex Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Focal Adhesion Mitochondrial Nucleoid Extracellular Exosome MIB Complex
	Molecular Function	Zinc Ion Binding Chaperone Binding	RNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Protein Folding Chaperone Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Protein Folding Protein Import Into Mitochondrial Matrix Protein Stabilization	Protein Export From Nucleus Inner Mitochondrial Membrane Organization Iron-sulfur Cluster Assembly Erythrocyte Differentiation Cellular Response To Unfolded Protein Protein Refolding Negative Regulation Of Apoptotic Process Regulation Of Erythrocyte Differentiation Negative Regulation Of Erythrocyte Differentiation Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Hematopoietic Stem Cell Differentiation Negative Regulation Of Hemopoiesis
Pathways			Mitochondrial protein import Regulation of HSF1-mediated heat shock response Cristae formation Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Fasting glucose ( 33402679 34059833) FEV1 ( 30804560) Glycated hemoglobin levels ( 34059833) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Joint damage in rheumatoid arthritis ( 26498133) Lung function (FVC) ( 28166213 30804560) Peak insulin response (insulin secretion adjusted) ( 28490609) Ulcerative colitis ( 28067908)	Autism spectrum disorder or schizophrenia ( 28540026) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Schizophrenia ( 25056061 29483656)
Interacting Genes		1 interacting genes: HSPA9	32 interacting genes: APP DNAJC19 DNLZ ERBB2 ERCC6 FGF1 GDF9 HSP90B1 HSPBP1 IL3 IL4 IL5 IL9 LAMTOR5 LINC01554 LSM8 MATK MVD NELFB OGT PTPN11 PTPRF SIRPA STUB1 SUMO2 SUMO4 SUPT6H TIMM44 TP53 XPO1 YKT6 YWHAG
Entrez ID		728489	3313
HPRD ID		19082	02770
Ensembl ID		ENSG00000213221	ENSG00000113013
Uniprot IDs		Q5SXM8	A0A384P5G6 P38646
PDB IDs			3N8E 4KBO 6NHK 6P2U 6PMT
Enriched GO Terms of Interacting Partners?
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