C2 and TNF

C2

TNF

Description complement C2 tumor necrosis factor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Advanced age-related macular degeneration ( 26691988)
  • Age at first sexual intercourse ( 34211149)
  • Age-related macular degeneration ( 20385819 20385826 23455636 21665990)
  • Age-related macular degeneration (choroidal neovascularisation) ( 22705344)
  • Age-related macular degeneration (geographic atrophy) ( 22705344)
  • Asthma ( 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Blood protein levels ( 29875488 28240269)
  • Body shape index ( 34021172)
  • Circulating myeloperoxidase levels (serum) ( 23620142)
  • Clostridioides difficle infection ( 33841421)
  • Coffee consumption ( 31046077)
  • Coronary artery disease ( 29212778 30104761)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Disease progression in age-related macular degeneration ( 29346644)
  • Early age-related macular degeneration ( 32843070)
  • Endometriosis ( 28881265)
  • Estimated glomerular filtration rate ( 31451708)
  • Estimated glomerular filtration rate in diabetes ( 31451708)
  • Hepatocellular carcinoma ( 21105107)
  • Hip circumference adjusted for BMI ( 34021172)
  • Inflammatory bowel disease ( 28067908)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Mosquito bite size ( 28199695)
  • Platelet aggregation ( 29185836)
  • Prostate cancer ( 23535732)
  • Sulfasalazine-induced agranulocytosis ( 28762467)
  • Systemic lupus erythematosus ( 24871463)
  • Ulcerative colitis ( 28067908)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • Youthful appearance (self-reported) ( 32339537)
Interacting Genes 15 interacting genes: C3 C4B C5 CREB3 EBP ERGIC3 FAM209A MASP1 MUC1 PSMA4 SEC11C SLC10A1 SLC35C2 STOM TNF 61 interacting genes: ADAM17 ADAM9 AQP3 BCL2L13 BGN BTNL9 C10orf67 C2 CBWD1 CCDC107 CCDC70 CLDN7 CLEC10A CREB3L1 CSF1 CYB5R3 DCN FAM209A FFAR2 FNDC9 FYN IFNG KASH5 KCNC4 LMNA LRRC25 LRRTM2 LYN MMP17 MOB1B MRM3 NFKBIA PAGE1 PANX1 PDIK1L PILRB PIP4P2 PLEKHO1 POU2F1 PPP1R11 PRTN3 RC3H1 RIPK1 RNF19B SEC61A1 SGCB SLC14A2 SLC30A4 SSMEM1 STOM STX1A TAPBP TMPRSS2 TNFRSF1A TNFRSF1B TNXB TRAF2 VSIR YWHAQ ZCCHC12 ZFP36
Entrez ID 717 7124
HPRD ID 08939 01855
Ensembl ID ENSG00000166278 ENSG00000232810
Uniprot IDs A0A0G2JL69 B4DQI1 B4DV48 P06681 Q53HP3 Q5JP69 Q8N6L6 P01375 Q5STB3
PDB IDs 2I6Q 2I6S 2ODP 2ODQ 3ERB 1A8M 1TNF 2AZ5 2E7A 2TUN 2ZJC 2ZPX 3ALQ 3IT8 3L9J 3WD5 4G3Y 4TSV 4TWT 4Y6O 5M2I 5M2J 5M2M 5MU8 5TSW 5UUI 5WUX 5YOY 6OOY 6OOZ 6OP0 6RMJ 6X81 6X82 6X83 6X85 6X86 7ASY 7AT7 7ATB 7JRA 7KP9 7KPA 7KPB
Enriched GO Terms of Interacting Partners?
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