TP73 and HECW2

  • Number of citations of the paper that reports this interaction (PubMedID 12890487)
  • 31
  • Data Source:
  • HPRD (in vivo, in vitro)

TP73

HECW2

Description tumor protein p73 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Joint damage in rheumatoid arthritis ( 31596875)
  • Visceral adipose tissue adjusted for BMI ( 22589738)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
  • Visceral fat ( 22589738)
  • Waist-hip ratio ( 28552196)
  • Heel bone mineral density ( 30598549)
  • Hip circumference adjusted for BMI ( 28552196)
  • Response to fenofibrate (LDL cholesterol levels) ( 27002377)
Interacting Genes 64 interacting genes: ABL1 ATF3 AURKA BIN1 BUB1B CABLES1 CCNB1 CCND1 CCNE1 CDK1 CDK2 CEBPZ CHD3 CREBBP CSNK2A1 DAXX DDB1 EP300 FBXO45 FLNA HCK HECW2 HIPK2 HIPK3 HMGB1 HRAS IKBKB ITCH KAT2B MAPK8 MDM2 MDM4 MTHFR MUL1 MYC NEDD4 NFYB PFDN5 PIAS1 PIN1 PLK1 PML PPP1R13B PRKACB RACK1 RANBP9 RCHY1 RPL11 RPL5 SIRT1 SMAD2 SMAD3 SP1 SP3 STUB1 SUMO1 TP53 TP63 TRIM28 UBE2I WT1 WWOX XPO1 YAP1 8 interacting genes: CBX1 CBX3 CBX5 FZR1 TP73 UBE2D2 UBE2D3 UBE2L3
Entrez ID 7161 57520
HPRD ID 03587 17099
Ensembl ID ENSG00000078900 ENSG00000138411
Uniprot IDs A0A0C4DFW9 A1PQX5 O15350 A0A2R8Y6F3 Q9P2P5
PDB IDs 1COK 1DXS 2KBY 2MPS 2NB1 2WQI 2WQJ 2WTT 2XWC 3VD0 3VD1 3VD2 4A63 4G82 4G83 4GUO 4GUQ 5HOB 5HOC 5KBD 6FGS 6IJQ 2LFE
Enriched GO Terms of Interacting Partners?
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