TNNT1 and OSBP2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		TNNT1	OSBP2
Description		troponin T1, slow skeletal type	oxysterol binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex	Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle Perinuclear Endoplasmic Reticulum Apical Dendrite
	Molecular Function	Protein Binding Tropomyosin Binding Troponin T Binding	Protein Binding Sterol Transporter Activity Cholesterol Binding Sterol Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction	Spermatid Development Sterol Transport
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS		Height ( 31562340)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine) ( 23648065) Estimated glomerular filtration rate change in renal transplantation (donor effect) ( 30920136) Red cell distribution width ( 32888494) Refractive error ( 32231278) Response to ketamine in bipolar disorder or major depression (antidepressant effects) ( 30552317) Takayasu arteritis ( 33308445)
Interacting Genes		69 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 CLIP4 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT27 KRT40 LARP1 LDOC1 MARS1 MORF4L1 MYOM2 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SBK3 SDCBP2 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TNNT2 TPM1 TPM3 TRA2A TRIM63 TSPYL2 TULP3 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768	6 interacting genes: DLG3 GOPC LNX1 PICK1 TNNT1 VIM
Entrez ID		7138	23762
HPRD ID		01841	09471
Ensembl ID		ENSG00000105048	ENSG00000184792
Uniprot IDs		P13805	Q969R2
PDB IDs
Enriched GO Terms of Interacting Partners?
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