TM4SF4 and GPR42

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TM4SF4	GPR42
Description		transmembrane 4 L six family member 4	G protein-coupled receptor 42
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Tissue Regeneration	G Protein-coupled Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 33339817) Alanine transaminase levels ( 29403010) Gallstone disease ( 30504769 27094239) Gamma glutamyl transferase levels ( 29403010 33339817) Ischemic stroke (large artery atherosclerosis) ( 29531354) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Serum alkaline phosphatase levels ( 33547301) Serum uric acid levels ( 30993211) Thyroid stimulating hormone levels ( 30367059 32769997) Urate levels ( 31578528)
Interacting Genes		22 interacting genes: APH1B CD79A CLEC17A CMTM2 CREB3 ERGIC3 FATE1 FFAR2 GJB1 GJB4 GJB5 GLP1R GPR101 GPR37L1 GPR42 GPX8 KCNK5 LHFPL5 OPRM1 SLC10A6 TBXA2R TMEM14B	104 interacting genes: ADIPOQ ALOX5AP ANKRD46 APOD ATP13A1 ATP4B ATP6V0B ATP6V0C BNIP3 BTN2A2 C1GALT1 CCDC167 CCL4L2 CD300C CD79A CLCA4 CLEC2D COMT CTXN3 CXCL16 CXCL9 DRAM1 EFNA5 EMP1 ERMP1 FAM3C FXYD3 FXYD6 GJB2 GOSR2 GPR37L1 GYPC IER3IP1 IGFBP5 IL1RL1 ITGAM JPH1 KCNA1 KLRG1 LAT LEPROTL1 LHFPL5 LNPEP LTC4S MFSD5 MFSD6 MGAM MS4A1 NDUFB11 NINJ2 NRM NSG1 PAEP PLP1 PLPP1 PMP22 PNLIPRP1 RPRM RTP2 RUSF1 SCD SERINC1 SERP2 SERTM1 SLC30A2 SLC30A3 SLC30A8 SLC35E4 SLC38A1 SLC38A7 SLC39A2 SLC41A1 SLC41A2 SMCO4 SMIM3 STATH STRIT1 STX8 SYNDIG1 SYNGR1 TEX264 TF TM4SF4 TMBIM6 TMEM140 TMEM147 TMEM182 TMEM19 TMEM237 TMEM239 TMEM242 TMEM262 TMEM30B TMEM60 TMEM65 TRARG1 TREX1 TSPO2 YIF1A YIPF1 YIPF2 YIPF4 YIPF6 ZFPL1
Entrez ID		7104	2866
HPRD ID		07585	16033
Ensembl ID		ENSG00000169903	ENSG00000126251
Uniprot IDs		P48230	A0A0K0PUY3 O15529
PDB IDs
Enriched GO Terms of Interacting Partners?
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