TLR3 and MAP2K6

  • Number of citations of the paper that reports this interaction (PubMedID 12609980)
  • 95
  • Data Source:
  • BioGRID (enzymatic study)

TLR3

MAP2K6

Description toll like receptor 3 mitogen-activated protein kinase kinase 6
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body shape index ( 34021172)
  • Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872)
  • Eye color ( 33692100)
  • Optic disc size ( 31809533)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy) ( 24554482)
  • Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225)
  • Waist-hip ratio ( 28552196)
Interacting Genes 10 interacting genes: CD14 CHEK2 CSK HLA-DRA MAP2K6 MYD88 RNF216 TICAM1 TICAM2 TRAF6 39 interacting genes: AKT1 BECN1 BRAF CCND2 CDKN2B DCTN1 EPHA2 FBXO7 FGFR4 GLIS2 HGF HRAS LRRK2 MAP2K3 MAP2K4 MAP2K5 MAP3K20 MAP3K4 MAP3K5 MAP3K7 MAPK1 MAPK12 MAPK13 MAPK14 MAPKAPK2 MLH1 NFE2L2 PICK1 PKN1 PLCB2 RAF1 RASSF1 RELA SMAD7 STAT4 STK11 TAOK2 TLR3 TRAF6
Entrez ID 7098 5608
HPRD ID 04324 03155
Ensembl ID ENSG00000164342 ENSG00000108984
Uniprot IDs O15455 A0A024R8K3 A8K3Y2 P52564
PDB IDs 1ZIW 2A0Z 2MK9 2MKA 3ULU 3ULV 5GS0 7C76 2Y8O 3ENM 3FME 3VN9 5ETF
Enriched GO Terms of Interacting Partners?
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