TK1 and COL4A2

  • Number of citations of the paper that reports this interaction (PubMedID 21900206)
  • 136
  • Data Source:
  • BioGRID (two hybrid)

TK1

COL4A2

Description thymidine kinase 1 collagen type IV alpha 2 chain
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase levels ( 33547301)
  • Apolipoprotein B levels ( 32203549)
  • Arterial stiffness ( 31070453)
  • Arterial stiffness index ( 31235810)
  • Blood urea nitrogen levels ( 31152163)
  • Body shape index ( 34021172)
  • Coronary artery calcification ( 22144573)
  • Coronary artery disease ( 32469254 29212778 24262325 26343387 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 21378990)
  • Diastolic blood pressure ( 27841878)
  • Fasting insulin ( 34059833)
  • Glomerular filtration rate ( 29403010)
  • Intake of sweets ( 31005972)
  • Ischemic stroke (small-vessel) ( 29531354)
  • LDL cholesterol ( 30275531)
  • LDL cholesterol levels ( 32203549)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Maximum retinal arteriolar tortuosity ( 31597446)
  • Middle temporal gyrus volume ( 31530798)
  • Monocyte count ( 32888494)
  • Myocardial infarction ( 26343387)
  • Night sleep phenotypes ( 27126917)
  • Non-lobar intracerebral hemorrhage ( 31430377)
  • Non-lobar intracerebral hemorrhage (MTAG) ( 31430377)
  • Periventricular white matter hyperintensities ( 32517579)
  • Platelet count ( 32888494)
  • Plateletcrit ( 32888494)
  • Retinal arteriolar tortuosity ( 31597446)
  • Septic shock (28-day mortality) ( 32755526)
  • Serum alkaline phosphatase levels ( 33547301)
  • Serum bilirubin levels x sex interaction in metabolic syndrome ( 30621171)
  • Total cholesterol levels ( 30275531)
  • Triglyceride levels ( 32203549)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • White matter hyperintensities ( 32358547)
  • White matter hyperintensity burden ( 25663218)
  • White matter hyperintensity volume ( 33293549)
  • White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
  • White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
Interacting Genes 163 interacting genes: A1BG A2M AAMP ABHD4 ACTB ACTL6B ACTR1B ADAMTS10 ADD1 AGAP1 ALAS1 ALB APLP1 APP ARFGAP1 ATG16L2 ATP5F1B ATP6V1A ATXN3 BAG6 BOLA2 BOLA2B CARHSP1 CCDC115 CCDC90B CDC20 CDK1 CDK4 CDKN1A CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE6 CRIP2 CRMP1 CSAD DACT1 DALRD3 DCAF13 DCAF7 DDAH2 DEAF1 DMPK DOCK7 DRAP1 DUS2 DYNC1I1 DYNC2I1 DYNLT2B EEF1A1 EIF3G EIF4A2 EIF6 ERG28 EXT2 EZH2 F13A1 FAF1 FAM20C FBN3 FGB FLAD1 FST GAPDH GDF9 GDI1 GET3 GLB1 GPCPD1 HADHB HERC3 HMGXB3 HSPBAP1 IER3IP1 IGHM IMMT INPP5K INTS11 ITSN1 JADE1 JMJD1C KDM6B KIF21B KIF5A KLHL23 KLHL5 KMT2B LRIF1 MAGEA4 MAST2 MED31 METTL23 MKI67 MPP1 MPPED1 MRFAP1 MRPL20-AS1 MRPL37 MSH2 NEUROD2 NGFR NKIRAS2 NMT2 NRBP1 ODC1 PAAF1 PDE4DIP PJA1 PKM PLD3 PLXNA3 PPP4C PROC PSME1 PTPN4 PTPRK QARS1 RBBP4 RBM48 REX1BD RPA1 RPL13 RPS2 RUVBL1 RXRA SDF4 SEMA5B SEPTIN6 SETDB1 SEZ6L2 SMC5 SNX1 SP110 SULT1A3 SUMO2 SUMO3 TAF1C THOC3 TIAM2 TLE1 TMSB4X TP53 TRIM46 TRMT2A TSC2 TTC38 TUBA1A TUBB2A TUBB3 TYK2 UNC119 UPF2 USP4 WDR18 WDR73 WIZ ZBTB16 ZNF431 ZXDC 24 interacting genes: ANTXR2 ANXA7 APP ATF7IP BGN BMP3 CD93 COL4A1 CSNK2B DAZAP2 FBLN2 FN1 HABP2 MATN2 MMP9 OSM SAA1 SERPINE2 SKIL SMN1 TENT5A TGFBI TK1 VHL
Entrez ID 7083 1284
HPRD ID 01771 00355
Ensembl ID ENSG00000167900 ENSG00000134871
Uniprot IDs A0A384MDV9 K7ES52 P04183 A0A024RDW8 P08572
PDB IDs 1W4R 1XBT 2ORV 2WVJ 1LI1 5NAX 5NB2 6MPX
Enriched GO Terms of Interacting Partners?
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