TCHH and HAX1

		TCHH	HAX1
Description		trichohyalin	HCLS1 associated protein X-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytosol Cytoskeleton	P-body Nuclear Envelope Transcription Regulator Complex Mitochondrion Mitochondrial Outer Membrane Mitochondrial Intermembrane Space Endoplasmic Reticulum Cell Cortex Actin Cytoskeleton Apical Plasma Membrane Sarcoplasmic Reticulum Lamellipodium Clathrin-coated Vesicle Nuclear Membrane
	Molecular Function	Calcium Ion Binding Transition Metal Ion Binding	Protein Binding Interleukin-1 Binding Protein N-terminus Binding
	Biological Process	Biological_process Keratinization Intermediate Filament Organization	Mitochondrion Organization Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Actin Filament Polymerization Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Kinase B Signaling Cellular Response To Cytokine Stimulus Regulation Of Autophagy Of Mitochondrion Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Actin Cytoskeleton Reorganization
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Common traits (Other) ( 20585627) Eczema ( 31361310) Hair morphology ( 19896111) Male-pattern baldness ( 28196072) Parent of origin effect on receptive language ability (paternal) ( 32635940) Scalp hair shape ( 26926045)	Bipolar disorder ( 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Mean spheric corpuscular volume ( 32888494) Nicotine dependence ( 28440896) Non-albumin protein levels ( 29403010) Reticulocyte count ( 32888494) Serum total protein level ( 29403010) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Triglyceride levels ( 32203549)
Interacting Genes		6 interacting genes: ADAM15 HAX1 PTGER4 SMCP UBAP2L UBC	28 interacting genes: ABCB1 ABCB11 ABCB4 BIRC3 CTTN DGKD EIF3F HCLS1 HNF4G IL1A KCNN3 KIAA0513 MAPK10 NEDD4L PKD2 POLR1D POLR1H PPP3CC PRNP RBX1 RNF217 RPA1 STAT5B SVIL TCHH UBAP2L YWHAQ ZNF420
Entrez ID		7062	10456
HPRD ID		19269	12075
Ensembl ID		ENSG00000159450	ENSG00000143575
Uniprot IDs		Q07283	A0A0S2Z565 A0A0S2Z591 O00165
PDB IDs
Enriched GO Terms of Interacting Partners?
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