TEK and SOCS1

  • Number of citations of the paper that reports this interaction (PubMedID 10022833)
  • 33
  • Data Source:
  • HPRD (two hybrid)

TEK

SOCS1

Description TEK receptor tyrosine kinase suppressor of cytokine signaling 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult asthma ( 27611488)
  • Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325)
  • Asthma ( 27611488)
  • Blood protein levels ( 30072576 29875488 28240269)
  • Blood protein levels in cardiovascular risk ( 28369058)
  • Cognitive decline (age-related) ( 28078323)
  • Coronary artery disease ( 29212778)
  • Gut microbiota relative abundance (unclassified genus belonging to family Lachnospiraceae) ( 33208821)
Interacting Genes 25 interacting genes: ANGPT1 ANGPT2 ANGPT4 ANGPTL1 APP CAV1 DOK2 DOK4 DUSP18 GRB14 GRB2 GRB7 IKBKG ILKAP PIK3R1 PTPN11 PTPRB PTPRR SHC1 SOCS1 STAT5A STAT5B STYX TIE1 TNIP2 54 interacting genes: AXL BLK COMMD1 CRK CSF1 CSF1R CUEDC2 CXCR4 CYTIP EGFR ELOB ELOC ERBB2 ERBB4 FLT3 FYN GHR GRB2 IFNAR1 IFNGR1 IGF1R IL2RB INSR IRF7 IRS1 IRS2 ITK JAK1 JAK2 JAK3 KIT LCK LYN MET MIR924HG MPL NCK1 PDGFRB PIK3R1 PIK3R2 PIM2 PTK2 RELA SH3GL1 SRC TEC TEK TIRAP TP53 TRIM8 TYK2 VAV1 VAV2 YES1
Entrez ID 7010 8651
HPRD ID 02571 04669
Ensembl ID ENSG00000120156 ENSG00000185338
Uniprot IDs Q02763 Q59HG2 O15524 Q4JHT5
PDB IDs 1FVR 2GY5 2GY7 2OO8 2OSC 2P4I 2WQB 3BEA 3L8P 4K0V 4X3J 5MYA 5MYB 5UTK 6MWE
Enriched GO Terms of Interacting Partners?
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