TEAD3 and VGLL4

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		TEAD3	VGLL4
Description		TEA domain transcription factor 3	vestigial like family member 4
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Transcription Regulator Complex	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Transcription Coactivator Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Female Pregnancy Hippo Signaling Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Asymmetric Neuroblast Division	Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Growth Negative Regulation Of Hippo Signaling Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Cellular Protein Catabolic Process
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription
Drugs
Diseases
GWAS		Birth weight ( 31043758) Colorectal cancer or advanced adenoma ( 30510241) Offspring birth weight ( 31043758)	Anorexia nervosa ( 21079607) Blond vs. brown/black hair color ( 30531825) Body mass index ( 28892062) Chronic obstructive pulmonary disease ( 30804561) Clopidogrel active metabolite levels ( 28207573) Height ( 25429064 31562340) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Male-pattern baldness ( 28196072) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Moderate-to-late spontaneous preterm birth ( 31194736) Offspring birth weight ( 31043758) Optic disc area ( 28073927) Relative hand skill in reading disability ( 24068947) Spontaneous preterm birth with premature rupture of membranes ( 31194736)
Interacting Genes		15 interacting genes: AP4S1 CTBP2 E2F1 E2F3 KIFC2 MYH7 PHB2 PIDD1 SUMO2 VGLL1 VGLL2 VGLL3 VGLL4 WWTR1 YAP1	11 interacting genes: CDK6 DAPK1 LRRK1 LRRK2 MEF2A MEF2C MFHAS1 TEAD1 TEAD2 TEAD3 TERF2IP
Entrez ID		7005	9686
HPRD ID		04411	11672
Ensembl ID		ENSG00000007866	ENSG00000144560
Uniprot IDs		Q99594	A0A075B6E4 A0A0A6YYI5 G5E9M7 G5E9M9 Q14135
PDB IDs		5EMW
Enriched GO Terms of Interacting Partners?
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