MLX and SAP30BP

Number of citations of the paper that reports this interaction (PubMedID 18255255)
9

Data Source:
BioGRID (two hybrid)

		MLX	SAP30BP
Description		MAX dimerization protein MLX	SAP30 binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Membrane	Nucleus Nucleoplasm Intermediate Filament Cytoskeleton
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Homodimerization Activity Protein Heterodimerization Activity Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription, DNA-templated Apoptotic Process Response To Virus Positive Regulation Of Histone Deacetylation Modulation By Host Of Symbiont Transcription
Pathways		ChREBP activates metabolic gene expression ChREBP activates metabolic gene expression	NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Type 2 diabetes ( 30297969 29632382 30718926) Type 2 diabetes (time to event) ( 32589924) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Rotator cuff tears ( 26350878)
Interacting Genes		31 interacting genes: APP BACH2 BEND7 CASK CCT6A DDIT4L GABARAPL1 GABARAPL2 ID3 KRTAP13-3 LNX1 LNX2 MAD1L1 MEI4 MEOX1 MEOX2 MLXIP MLXIPL MNT MXD1 MXD4 PIAS2 RBM39 RHBDD2 SAP30BP TEPSIN TLE5 TNNT2 UBE2I ZBTB32 ZNF620	26 interacting genes: CCNL1 CSNK2A1 DHX8 FHL2 FHL3 FRA10AC1 GOLGA2 GSK3B MLX OGT PRKAR1B PUF60 RBM17 RBM39 RPS6KA6 SAP30 SNCA SUPT5H TFIP11 THAP1 THOC1 U2AF2 WDR77 WDR83 ZNF212 ZNF408
Entrez ID		6945	29115
HPRD ID		04278	17094
Ensembl ID		ENSG00000108788	ENSG00000161526
Uniprot IDs		Q9UH92	A0A024R8R0 Q9UHR5
PDB IDs
Enriched GO Terms of Interacting Partners?
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