TBXA2R and ARL6IP6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TBXA2R	ARL6IP6
Description		thromboxane A2 receptor	ADP ribosylation factor like GTPase 6 interacting protein 6
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Plasma Membrane Integral Component Of Plasma Membrane Nuclear Speck	Nuclear Inner Membrane Integral Component Of Membrane
	Molecular Function	Thromboxane A2 Receptor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding
	Biological Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Nutrient Response To Xenobiotic Stimulus Second-messenger-mediated Signaling Positive Regulation Of Blood Coagulation Response To Testosterone Thromboxane A2 Signaling Pathway Response To Ethanol Positive Regulation Of Angiogenesis Positive Regulation Of Blood Pressure Positive Regulation Of Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Regulation Of Catalytic Activity Cellular Response To Lipopolysaccharide Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Pathways		Prostanoid ligand receptors G alpha (q) signalling events G alpha (12/13) signalling events Thromboxane signalling through TP receptor
Drugs		Ridogrel Seratrodast Morniflumate
Diseases
GWAS			Lung cancer ( 28604730) Pancreatic cancer ( 29422604) Recurrent major depressive disorder x sex interaction ( 34099189) Refractive error ( 32231278)
Interacting Genes		35 interacting genes: ADIPOR1 ARL6IP6 C5orf46 EMP1 GJB2 GNA11 GNA12 GNA13 GNAI2 GNAQ GNAS GNB1 GNG2 GPRASP1 GRK5 GRK6 MFSD5 MS4A13 NME2 NOX1 PRDX4 PRKCA PSMA7 PSME3 PTGIR RAB11A RACK1 RAF1 RPGRIP1L SLC35B4 SLC41A1 TM4SF4 VRK2 YWHAZ ZDHHC15	19 interacting genes: APP AQP6 ARL6 CLRN2 CMTM2 DRD2 EBP FMNL2 GJA8 GPR61 MGST3 RBM43 RUSF1 SLC10A1 TBXA2R TIMMDC1 TMEM205 TMEM80 TMEM86B
Entrez ID		6915	151188
HPRD ID		01768	12485
Ensembl ID		ENSG00000006638	ENSG00000177917
Uniprot IDs		P21731 Q05C92 Q0VAB0	B3KMZ5 Q8N6S5
PDB IDs		1LBN
Enriched GO Terms of Interacting Partners?
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