TAP1 and ERVFRD-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TAP1	ERVFRD-1
Description		transporter 1, ATP binding cassette subfamily B member	endogenous retrovirus group FRD member 1, envelope
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Phagocytic Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Centriolar Satellite MHC Class I Peptide Loading Complex TAP Complex	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding ATP Binding ABC-type Peptide Antigen Transporter Activity ABC-type Peptide Transporter Activity MHC Class Ib Protein Binding MHC Class I Protein Binding Peptide Antigen Binding ATPase-coupled Transmembrane Transporter Activity Protein Homodimerization Activity ADP Binding Metal Ion Binding TAP1 Binding TAP2 Binding Peptide Transmembrane Transporter Activity	Protein Binding
	Biological Process	Adaptive Immune Response Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Defense Response Protein Transport Peptide Transport Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Cytosol To Endoplasmic Reticulum Transport Transmembrane Transport	Syncytium Formation By Plasma Membrane Fusion Syncytium Formation Myoblast Fusion
Pathways		ER-Phagosome pathway ER-Phagosome pathway Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS		Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Hip circumference adjusted for BMI ( 34021172) IgA nephropathy ( 25305756) Metabolite levels ( 23823483) Nephropathy ( 21399633)
Interacting Genes		27 interacting genes: AQP6 CHRM3 CREB3 ERGIC3 ERVFRD-1 ESR1 GEMIN4 GPR152 HLA-F HLA-G KRTAP4-12 LCE2C LMNA MDFI MUL1 PDIA3 PSMB5 PSMB8 RNF19B SLC10A1 SLC10A6 SLC35C2 SSMEM1 TAP2 TAPBP TDP2 TMEM14B	15 interacting genes: APP BCL2L2 CCL4L2 ERMP1 FXR1 GPHB5 MIP NINJ2 NXPE3 PAEP SEC22A SLC30A8 SLC41A2 TAP1 TMPRSS4
Entrez ID		6890	405754
HPRD ID		01359	13648
Ensembl ID		ENSG00000168394	ENSG00000244476
Uniprot IDs		A0A0S2Z5A6 B7Z7P4 Q03518 X5CKB3	P60508
PDB IDs		1JJ7 5U1D	1Y4M 6RX3
Enriched GO Terms of Interacting Partners?
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