BTF3 and MED21

Number of citations of the paper that reports this interaction (PubMedID 2320128)
43

Data Source:
HPRD (in vitro)

		BTF3	MED21
Description		basic transcription factor 3	mediator complex subunit 21
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Nascent Polypeptide-associated Complex Polysomal Ribosome	Ubiquitin Ligase Complex Mediator Complex
	Molecular Function	RNA Binding Protein Binding	Transcription Coregulator Activity Transcription Coactivator Activity DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	In Utero Embryonic Development Transcription By RNA Polymerase II Protein Transport	Blastocyst Development Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination Stem Cell Population Maintenance RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II
Pathways			PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Monobrow thickness ( 26926045)	Dimensional psychopathology (Social) ( 29496196)
Interacting Genes		14 interacting genes: APP CDC42 CSNK2B IFTAP MED21 NAA40 NMT2 NOTO POLR2B PTGIS TXLNA TXLNB USP16 ZDHHC17	30 interacting genes: BLOC1S6 BORCS6 BRCA1 BTF3 CDK8 CDK9 ELOA ESR1 ESR2 HGS HNF4A HTT MAGEA6 MAGEB4 MED29 MIEF1 PCBD2 POLR2A SKP1 SSC5D TARBP2 TFG THRA THRB TP53 TRIM27 TRIM72 VAV2 ZNF655 ZSCAN1
Entrez ID		689	9412
HPRD ID		03966	09156
Ensembl ID		ENSG00000145741	ENSG00000152944
Uniprot IDs		P20290	A0A024RAW0 Q13503
PDB IDs		3LKX 3MCB
Enriched GO Terms of Interacting Partners?
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